WEKO3
アイテム
Building atomic model of overlapping dinucleosome from SAXS and SANS data.
https://repo.qst.go.jp/records/76801
https://repo.qst.go.jp/records/768019fdbcb58-9308-46d4-97bf-da34ecae4055
| Item type | 会議発表用資料 / Presentation(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2019-08-15 | |||||
| タイトル | ||||||
| タイトル | Building atomic model of overlapping dinucleosome from SAXS and SANS data. | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_c94f | |||||
| 資源タイプ | conference object | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Matsumoto, Atsushi
× Matsumoto, Atsushi× Matsumoto, Atsushi |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | To understand functional feature of overlapping di-nucleosome (OLDN), the solution structure was investigated with the integration of small-angle X-ray and neutron scatterings (SAXS and SANS), computer modeling and molecular dynamics simulations. We found that inclusion of histone tails which are not observed in the crystal structure essentially improves the model quality. The obtained structural models indicate that OLDN adopts a relatively large variety of conformations, each of which is stabilized by the histone tails placed in the interface between the hexasome and the octasome to form hydrogen bonds with DNA. | |||||
| 会議概要（会議名, 開催地, 会期, 主催者等） | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | Marriage of computational and experimental techniques for solution small-angle scattering | |||||
| 発表年月日 | ||||||
| 日付 | 2019-09-13 | |||||
| 日付タイプ | Issued | |||||
