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Compton-PET Imaging of 10C for Range Verification of Carbon Ion Therapy

https://repo.qst.go.jp/records/76756
https://repo.qst.go.jp/records/76756
dcdece69-6daa-4575-97a8-09bf58d3a212
Item type 会議発表論文 / Conference Paper(1)
公開日 2019-09-12
タイトル
タイトル Compton-PET Imaging of 10C for Range Verification of Carbon Ion Therapy
言語
言語 eng
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_5794
資源タイプ conference paper
アクセス権
アクセス権 metadata only access
アクセス権URI http://purl.org/coar/access_right/c_14cb
著者 Mohammadi, Akram

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WEKO 782995

Mohammadi, Akram

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Yoshida, Eiji

× Yoshida, Eiji

WEKO 782996

Yoshida, Eiji

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Okumura, Yusuke

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WEKO 782997

Okumura, Yusuke

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Nitta, Munetaka

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WEKO 782998

Nitta, Munetaka

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Nishikido, Fumihiko

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WEKO 782999

Nishikido, Fumihiko

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Kitagawa, Atsushi

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WEKO 783000

Kitagawa, Atsushi

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kamada, Kei

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WEKO 783001

kamada, Kei

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Parodi, Katia

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WEKO 783002

Parodi, Katia

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Yamaya, Taiga

× Yamaya, Taiga

WEKO 783003

Yamaya, Taiga

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Mohammadi, Akram

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WEKO 783004

en Mohammadi, Akram

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Yoshida, Eiji

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WEKO 783005

en Yoshida, Eiji

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Okumura, Yusuke

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WEKO 783006

en Okumura, Yusuke

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Nitta, Munetaka

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WEKO 783007

en Nitta, Munetaka

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Nishikido, Fumihiko

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WEKO 783008

en Nishikido, Fumihiko

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Kitagawa, Atsushi

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WEKO 783009

en Kitagawa, Atsushi

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Parodi, Katia

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WEKO 783010

en Parodi, Katia

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Yamaya, Taiga

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WEKO 783011

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抄録
内容記述タイプ Abstract
内容記述 In carbon ion therapy, visualization of the range of incident particles in a patient body is important for treatment verification. In-beam positron emission tomography (PET) imaging in ion therapy is one of the method for verification of treatment due to the high quality of PET images. We have already shown the feasibility of radioactive beams of 15 O and 11 C using in-beam PET imaging using our OpenPET system. Recently, we have developed a whole gamma imaging (WGI) system which can work as PET, single gamma-ray and triple gamma-ray imaging simultaneously. The WGI system has high potential to detect location of 10 C, which emits positron with a simultaneous gamma-ray of 718 keV, and activity of other produced positron emitting nuclei within patient body during ion therapy. In this work, we focus on investigation of performance of WGI system for 10 C irradiation. First, the performance of scatterer detector of the WGI system regarding the radiation hardness was studied for 10 C irradiation, then the performance of WGI was studied by simulation using the Geant4 code. The scatterer detector consisted of a segmented GAGG crystal and a multi-pixel photon counter (MPPC) and its performance was studied as a PMMA phantom was irradiated with 5 and 400 spills of 10 C with energy of 350 MeV/u. No damage to the MPPC (scatterer detector) was observed even though after irradiation of 400 spills (~1.9×10 5 particle per spill). Sensitivity values of WGI system by simulation of a 10 C nuclide at the center of field of view (FOV) for PET mode imaging, single gamma-ray of 718 keV imaging and triple gamma-ray imaging were 7.85%, 0.28% and 0.012% respectively. The performance of WGI system is going to be evaluated for 10 C irradiation in the near future.
書誌情報 2018 IEEE Nuclear Science Symposium and Medical Imaging Conference Proceedings (NSS/MIC)

発行日 2019-09
出版者
出版者 IEEE
DOI
識別子タイプ DOI
関連識別子 10.1109/NSSMIC.2018.8824325
関連サイト
識別子タイプ URI
関連識別子 https://ieeexplore.ieee.org/document/8824325
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