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Engineering the Interface: Nanodiamond Coating on 3D-Printed Titanium Promotes Mammalian Cell Growth and Inhibits Staphylococcus aureus Colonization
https://repo.qst.go.jp/records/76723
https://repo.qst.go.jp/records/76723f01f4743-0b26-4cc4-99ed-b9c4212f26e7
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2019-09-10 | |||||
| タイトル | ||||||
| タイトル | Engineering the Interface: Nanodiamond Coating on 3D-Printed Titanium Promotes Mammalian Cell Growth and Inhibits Staphylococcus aureus Colonization | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Rifai, A.
× Rifai, A.× Tran, N.× Reineck, P.× Elbourne, A.× Mayes, E.× Sarker, A.× Dekiwadia, C.× P. Ivanova, E.× J. Crawford, R.× Ohshima, Takeshi× C. Gibson, B.× D. Greentree, A.× Pirogova, E.× Fox, K.× Ohshima, Takeshi |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Additively manufactured selective laser melted titanium (SLM-Ti) can open the possibility of tailored medical implants for patients. IN spite of orthopedic implant advancements, significant problems remain with regard to suboptimal osseointegration at the interface between the implant and the surrounding tissue. This study shows that applying a nanodiamond (ND) coating onto SLM-Ti scaffolds provides an improved surface for mammalian cell growth while inhibiting colonization of Staphylococcus aureus bacteria. Because of the simplicity of our methodology, the approach is suitable for coating SLM-Ti geometries. The ND coating demonstrated 32 and 29% increases in cell density of human dermal fibroblasts and osteoblasts, respectively, after 3 days of incubation compared with the uncoated SLM-Ti substratum. This study paves a way to create facile antifouling SLM-Ti structures for biomedical implants. |
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| 書誌情報 |
ACS Applied Materials and Interfeces 巻 11, 号 27, p. 24588-24597, 発行日 2019-09 |
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| 出版者 | ||||||
| 出版者 | ACS publications | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 1944-8244 | |||||
| DOI | ||||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.1021/acsami.9b07064 | |||||
| 関連サイト | ||||||
| 識別子タイプ | URI | |||||
| 関連識別子 | https://pubs.acs.org/doi/10.1021/acsami.9b07064 | |||||
