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High-precision Compton imaging of 4.4 MeV prompt gamma-ray toward an on-line monitor for proton therapy
https://repo.qst.go.jp/records/76671
https://repo.qst.go.jp/records/7667124db848a-f760-4ba9-90e3-c6f2c43ba292
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2019-09-05 | |||||
| タイトル | ||||||
| タイトル | High-precision Compton imaging of 4.4 MeV prompt gamma-ray toward an on-line monitor for proton therapy | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Mochizuki, S.
× Mochizuki, S.× Kataoka, J.× Koide, A.× Fujieda, K.× Maruhashi, T.× Kurihara, T.× Sueoka, K.× Tagawa, L.× Yoneyama, M.× Inaniwa, Taku× Inaniwa, Taku |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Proton therapy is a widely used and effective treatment for cancer. A high-dose concentration of proton beam reduces damage to normal tissues. However, it also requires a high accuracy of irradiation. PET is generally used to verify the proton range after irradiation, but, the distributions of positrons and the energy deposited by protons are not similar to each other. Recently, prompt gamma-ray imaging has attracted attention as a new, online imaging technique. In particular, 4.4 MeV gamma rays emitted from 12C* is one of the best probes to monitor the proton dose, however imaging techniques are far from established. We have developed a novel, 3-D position sensitive Compton camera based on Ce:GAGG scintillators coupled with multi-pixel photon counter (MPPC) arrays, thus making it optimized for imaging in the 1–10 MeV range. The angular resolution is 5 degrees (FWHM) at 4.4 MeV. We have established various methods to discriminate multiple-Compton and escape events, both of which can be critical backgrounds for precise imaging of prompt gamma rays. By irradiating a 70 MeV proton beam on the PMMA phantom, we demonstrated that 4.4 MeV gamma ray image is sharply concentrated on the Bragg peak, as was expected from the PHITS simulation. |
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| 書誌情報 |
Nuclear Instruments and Methods in Physics Research Section A 巻 936, p. 43-45, 発行日 2019-08 |
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| 出版者 | ||||||
| 出版者 | Elsevier | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 0168-9002 | |||||
| DOI | ||||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.1016/j.nima.2018.11.032 | |||||
| 関連サイト | ||||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | https://doi.org/10.1016/j.nima.2018.11.032 | |||||
