WEKO3
アイテム
Range verification of radioactive ion beams of C-11 and O-15 using in-beam PET imaging
https://repo.qst.go.jp/records/76289
https://repo.qst.go.jp/records/76289f6707c84-7058-43a9-8814-f7fdd793bf25
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2019-07-17 | |||||
| タイトル | ||||||
| タイトル | Range verification of radioactive ion beams of C-11 and O-15 using in-beam PET imaging | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Mohammadi, Akram
× Mohammadi, Akram× Tashima, Hideaki× Iwao, Yuma× Takyu, Sodai× Akamatsu, Go× Nishikido, Fumihiko× Yoshida, Eiji× Kitagawa, Atsushi× Parodi, Katia× Yamaya, Taiga× Mohammadi, Akram× Tashima, Hideaki× Iwao, Yuma× Takyu, Sodai× Akamatsu, Go× Nishikido, Fumihiko× Yoshida, Eiji× Kitagawa, Atsushi× Parodi, Katia× Yamaya, Taiga |
|||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | In advanced ion therapy, the visualization of the range of incident ions in a patient’s body is important for exploiting the advantages of this type of therapy. It is ideal to use radioactive ion beams for in-beam positron emission tomography (PET) imaging in particle therapy due to the high quality of PET images caused by the high signal-to-noise ratio. We have shown the feasibility of this idea through an in-beam PET study for 11C and 15O ion beams using the dedicated OpenPET system. In this work, we investigate the potential difference between the Bragg peak position and the position of the maximum detected positron-emitting fragments by a PET system for the radioactive beams of 11C and 15O. For this purpose, we measured the depth dose in a water phantom and performed PET scans of an irradiated PMMA phantom for the available beams of 11C and 15O at the Heavy Ion Medical Accelerator in Chiba (HIMAC). Then, we simulated the depth dose profiles in the water phantom and the yield of the positron-emitting fragments in a PMMA phantom for both available beams using the Monte Carlo code PHITS. The positions of the Bragg peak and maximum positron emitting fragments from the measurements were well reproduced by simulation. The effect of beam energy broadening on the positional differences between two peaks was studied by simulating an irradiated PMMA phantom. The differences in position between the Bragg peak and the maximum positron-emitting fragments increased when the beam energy spread was broadened, although the differences were zero for the ideal mono-energetic beams. Greater differences were observed for 11C ion beams compared to 15O ion beams, although both beams had the same range in water, and the higher energy corresponded to a larger difference. For the known energy spread of the beams, the predicted differences between two peaks from the simulation were consistent with the measured data within submillimetre agreement. |
|||||
| 書誌情報 |
Physics in Medicine & Biology 巻 64, 号 14, p. 145014-1-145014-9, 発行日 2019-07 |
|||||
| 出版者 | ||||||
| 出版者 | IOP Publishing | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 0031-9155 | |||||
| PubMed番号 | ||||||
| 識別子タイプ | PMID | |||||
| 関連識別子 | 31146265 | |||||
| DOI | ||||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.1088/1361-6560/ab25ce | |||||
| 関連サイト | ||||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | https://doi.org/10.1088/1361-6560/ab25ce | |||||
