WEKO3
アイテム
Evaluation of Poly-MVA as a new radio-protectant against high LET particle irradiation
https://repo.qst.go.jp/records/75702
https://repo.qst.go.jp/records/7570255348ce1-45a8-4c31-8fb0-0b70b5b5ceb9
| Item type | 会議発表用資料 / Presentation(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2019-04-19 | |||||
| タイトル | ||||||
| タイトル | Evaluation of Poly-MVA as a new radio-protectant against high LET particle irradiation | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_c94f | |||||
| 資源タイプ | conference object | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
ZHOU , Guangming
× ZHOU , Guangming× Wang, Bing× Hirayama, Ryoichi× Wu, Anqing× Hu, Wentao× Zhang, Jian× Ziyang, Guo× Liu, Cuihua× Katsube, Takanori× Nenoi, Mitsuru× Li, Bingyan× Pei, Hailong× Zhou, Guangming× Wang, Bing× Hirayama, Ryoichi× Wu, Anqing× Hu, Wentao× Zhang, Jian× Ziyang, Guo× Liu, Cuihua× Katsube, Takanori× Nenoi, Mitsuru× Li, Bingyan× Pei, Hailong |
|||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Ploy MVA was evaluated for its potential to protect mouse from radiation. Treatment of 8 Gy X-ray-irradiated mice with polyMVA increased survival rate to 100% 30 days after irradiation. The best effect was based on adequate absorption of ployMVA by a health mouse intestine. Doses higher than 8 Gy X-rays or 5.5 Gy carbon ions induce serious intestinal injury, which caused impedient absorption of ployMVA. We found simple ployMVA treatment was ineffective in protecting mice from carbon ion irradiation of doses higher than 5.5 Gy. However, the synergistic effect of ployMVA and Amifostine against irradiation deserves further exploration. In the FY 2018, we have plotted a credible survival fraction of the mice exposed to X-ray irradiation, which has laid the foundation for the heavy ion experiments. | |||||
| 会議概要（会議名, 開催地, 会期, 主催者等） | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | 平成30年度放射線医学総合研究所重粒子線がん治療装置等共同利用研究報告会 | |||||
| 発表年月日 | ||||||
| 日付 | 2019-04-22 | |||||
| 日付タイプ | Issued | |||||
