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The Functions of O-GlcNAc in Pluripotent Stem Cells
https://repo.qst.go.jp/records/75663
https://repo.qst.go.jp/records/75663fbf8be9c-7907-4eef-8d42-b421b48da798
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2019-04-21 | |||||
| タイトル | ||||||
| タイトル | The Functions of O-GlcNAc in Pluripotent Stem Cells | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
三浦, 太一
× 三浦, 太一× 西原, 祥子× Miura, Taichi |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | O-linked N-acetylglucosaminylation (O-GlcNAcylation) is a glycosylation characterized by the attachment of a single N-acetylglucosamine (GlcNAc) to the serine/threonine residues of nuclear, mitochondrial, and cytoplasmic proteins. Proteins modified by O-GlcNAc include signaling components, transcription factors, epigenetic regulators, and histones. O-GlcNAc has various functions such as inhibition of phosphorylation, regulation of transcriptional activity, stabilization of proteins, and regulation of intracellular localization. In recent years, O-GlcNAc has been drawing attention as a key factor for regulating the undifferentiated/differentiated state in mouse/human pluripotent stem cells, and the functions of O-GlcNAc have been gradually clarified. | |||||
| 書誌情報 |
Trends in Glycoscience and Glycotechnology 巻 31, 号 180, p. E69-E75, 発行日 2019-05 |
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| 出版者 | ||||||
| 出版者 | FCCA | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 0915-7352 | |||||
| DOI | ||||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.4052/tigg.1954.2E | |||||
| 関連サイト | ||||||
| 識別子タイプ | URI | |||||
| 関連識別子 | https://www.jstage.jst.go.jp/article/tigg/31/180/31_1954.2E/_article | |||||
