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The Monte Carlo simulation for lateral radiation quality of carbon ion beam with the empirical model
https://repo.qst.go.jp/records/75621
https://repo.qst.go.jp/records/75621dfb3c6d9-905f-4d51-9cef-d51d620ab889
| Item type | 会議発表用資料 / Presentation(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2019-04-17 | |||||
| タイトル | ||||||
| タイトル | The Monte Carlo simulation for lateral radiation quality of carbon ion beam with the empirical model | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_c94f | |||||
| 資源タイプ | conference object | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
中路, 拓
× 中路, 拓× Nakaji, Taku |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | [Purpose] Carbon ion (C-ion) radiotherapy is better than the external photon radiotherapy because of C-ion’s higher concentration of dose and greater biological effects on the peripheral area of Bragg peak. The scanning method can realize the ideal shape of dose distribution for a coverage of target. It is important for passive method with a broad-beam to consider the radiation quality only along with depth for relative biological effectiveness (RBE). However, the lateral distribution of C-ion beam’s radiation quality must be considered for using scanning irradiation to confirm the uniformity of biological dose. In this study, the lateral radiation quality of C-ion beams is shown with the empirical model for biological dose estimation. [Method] The lateral dose, dose-averaged LET- (LETd) and RBE-distribution for of monochrome C-ion pencil beam with three incident kinetic energy (230, 290, 350 MeV/u) were derived with Monte Carlo tool Geant4.10.01.p03, respectively. The RBE as a biological index was calculated with a mixed-beam model, which is an empirical model developed by NIRS. [Results] The more the kinetic energy increases, the more dose distribution of primary C-ion beam spread from 10 mm to 16 mm in Bragg peak area, which looks like three-Gaussian. While the shape of RBE-distribution is similar to dose one, LETd distribution looks like a shape of well, which has a peak region at around 5 to 10 mm of radius. [Discussion] The C-ion has known as a high-LET particle around Bragg peak, it’s especially about beam’s depth direction. Although the lateral distribution had been not known well, the LETd distribution became obvious as a well-shape distribution in this study. The lateral radiation quality is critical for a spot scanning method because the biological dose distribution must be conformed three-dimensionally about a number of spot, which is not like broad-beam method. [Conclusion] We showed the lateral distributions of C-ion beams. These results may help you get the knowledge to understand the biological effects of spot scanning method. |
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| 会議概要（会議名, 開催地, 会期, 主催者等） | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | 117th Scientific Meeting of JSMP | |||||
| 発表年月日 | ||||||
| 日付 | 2019-04-12 | |||||
| 日付タイプ | Issued | |||||
