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Development of a CT-number parameterization method and validation for Monte Carlo simulation of carbon-ion radiotherapy: A preliminary study

https://repo.qst.go.jp/records/75611
https://repo.qst.go.jp/records/75611
664b8cbb-618a-40c6-8629-f29b258c123e
Item type 会議発表用資料 / Presentation(1)
公開日 2019-04-16
タイトル
タイトル Development of a CT-number parameterization method and validation for Monte Carlo simulation of carbon-ion radiotherapy: A preliminary study
言語
言語 eng
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_c94f
資源タイプ conference object
アクセス権
アクセス権 metadata only access
アクセス権URI http://purl.org/coar/access_right/c_14cb
著者 Chang, Weishan

× Chang, Weishan

WEKO 756324

Chang, Weishan

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Koba, Yusuke

× Koba, Yusuke

WEKO 756325

Koba, Yusuke

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Furuta, Takuya

× Furuta, Takuya

WEKO 756326

Furuta, Takuya

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Yonai, Shunsuke

× Yonai, Shunsuke

WEKO 756327

Yonai, Shunsuke

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Hasimoto, Shintaro

× Hasimoto, Shintaro

WEKO 756328

Hasimoto, Shintaro

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Matsumoto, Shinnosuke

× Matsumoto, Shinnosuke

WEKO 756329

Matsumoto, Shinnosuke

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Sato, Tatsuhiko

× Sato, Tatsuhiko

WEKO 756330

Sato, Tatsuhiko

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Chang, Weishan

× Chang, Weishan

WEKO 756331

en Chang, Weishan

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Koba, Yusuke

× Koba, Yusuke

WEKO 756332

en Koba, Yusuke

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Yonai, Shunsuke

× Yonai, Shunsuke

WEKO 756333

en Yonai, Shunsuke

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Matsumoto, Shinnosuke

× Matsumoto, Shinnosuke

WEKO 756334

en Matsumoto, Shinnosuke

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抄録
内容記述タイプ Abstract
内容記述 Purpose: Most treatment planning system (TPS) used in carbon-ion radiotherapy (CIRT) facilities are implemented with pencil beam algorithm which cannot compute dose by secondary particle and neutron dose to whole body while these dose are thought to be the reasons of radiation-induced secondary cancer. In this work, we evaluated the CT conversion method and the accuracy of the beam modeling of a developing dedicated framework using Monte Carlo (MC) simulation code PHITS for retrospective analysis of CIRT.
Materials and methods: For consistency to the TPS, the CT number to stopping power ratio table used in TPS and the standard tissues of reference adult phantoms published in ICRP-110 were used to converse CT number to density and material composition. To verify the conversion methods corresponding to the TPS, we calculated the depth dose distribution in ten different material by TPS and MC and compared the range.
A 400 MeV/n carbon beam with an 8 cm SOBP was used for verifying the beam model in MC. Advanced Markus chamber and pin-point chamber were used for depth dose distribution and lateral dose distribution, respectively. In addition to dose distribution inside of field, the out-filed dose distribution was also compared in this work.
Results: For all the range difference between TPS and MC are within 1 mm, while the dose difference are shown in some material with high CT number. The measured range agreed well with the range calculated by TPS and MC while significant dose difference in the fragmentation tail behind the Bragg peak was found when a relatively thick range shifter was implanted.
Conclusion: In this work, the CT conversion method and the accuracy of the beam modeling of a developing dedicated framework for retrospective analysis of CIRT were evaluated.
会議概要(会議名, 開催地, 会期, 主催者等)
内容記述タイプ Other
内容記述 第117回日本医学物理学会学術大会
発表年月日
日付 2019-04-12
日付タイプ Issued
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