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Performance characterization of a new whole-body PET prototype with four-layer DOI detectors
https://repo.qst.go.jp/records/75607
https://repo.qst.go.jp/records/75607dd2695a1-cc48-41cf-8884-8c7fec20b924
| Item type | 会議発表用資料 / Presentation(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2019-04-15 | |||||
| タイトル | ||||||
| タイトル | Performance characterization of a new whole-body PET prototype with four-layer DOI detectors | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_c94f | |||||
| 資源タイプ | conference object | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
赤松, 剛
× 赤松, 剛× 田島, 英朗× 岩男, 悠真× 脇坂, 秀克× 前田, 貴雅× Akram, Mohammadi× 田久, 創大× 錦戸, 文彦× 吉田, 英治× 山谷, 泰賀× Akamatsu, Go× Tashima, Hideaki× Iwao, Yuma× Wakizaka, Hidekatsu× Maeda, Takamasa× Mohammadi, Akram× Takyu, Sodai× Nishikido, Fumihiko× Yoshida, Eiji× Yamaya, Taiga |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | [Purpose] Depth-of-interaction (DOI) detection is a promising solution to improve the spatial resolution and its uniformity over the entire field-of-view (FOV). Although DOI detection technologies have been used in small ring PET systems, the impact of DOI technology on imaging performance of “whole-body” PET scanners has not been studied well. In this study, we evaluated the performance characteristics of our 4-layer DOI whole-body PET prototype scanner with particular focus on the impact of incorporating DOI information on the imaging performance. [Methods] Our whole-body DOI-PET prototype scanner had 4 detector rings, each of which consisted of 40 detectors (160 detectors in total). Each detector was composed of 1,024 GSOZ crystals, which were arranged in 4 layers of 16 × 16 arrays. The axial FOV was 215 mm and the ring diameter was 660 mm. We measured performance characteristics of the scanner according to the NEMA NU2 standard. In addition, we examined the impact of DOI information on the imaging performance using the NEMA NU4 image quality phantom. Three types of images were reconstructed with 4-layer DOI information, with virtual 2-layer DOI information, and without DOI information. [Results] The radial spatial resolution (FBP) was 4.1, 4.8 and 5.9 mm at 1, 10 and 20 cm offset position. The 4-layer DOI information improved the radial spatial resolution by 48% at the 20 cm offset position. The scatter fraction was 44% and the peak NECR was 22.9 kcps at 7.4 kBq/mL. The sensitivity was 5.9 kcps/MBq. For the NEMA NU4 image quality test at the 20 cm offset position, the image with 4-layer DOI information could visualize the smallest 1-mm-diameter hot cylinder. [Conclusion] We showed that the 4-layer DOI technology provided high and uniform spatial resolution over the FOV and improved the contrast for small uptake regions located at the peripheral FOV, which could improve detectability of small and distal lesions such as nodal metastases, especially in obese patients. |
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| 会議概要（会議名, 開催地, 会期, 主催者等） | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | 第117回日本医学物理学会学術大会 | |||||
| 発表年月日 | ||||||
| 日付 | 2019-04-11 | |||||
| 日付タイプ | Issued | |||||
