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Biological Dose Comparison between a Fixed RBE and a variable RBE in SFO and MFO IMPT with Various Multi-Beams for Brain Cancer
https://repo.qst.go.jp/records/75530
https://repo.qst.go.jp/records/75530ad59f19e-ef72-4e80-8152-a58b1039802b
Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2019-04-02 | |||||
タイトル | ||||||
タイトル | Biological Dose Comparison between a Fixed RBE and a variable RBE in SFO and MFO IMPT with Various Multi-Beams for Brain Cancer | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
アクセス権 | ||||||
アクセス権 | metadata only access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
著者 |
河野, 良介
× 河野, 良介× Cao, Wenhua× Yepes, Pablo× Bai, Xuemin× Poenisch, Falk× R.Grosshans, David× Akimoto, Tetsuo× Mohan, Radhe× Kohno, Ryosuke |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | IMPT plans with various multi-angle beams were planned by the Varian Ec- lipse treatment planning system for one case of brain cancer. Dose distribu- tions for each plan, along with the associated linear energy transfer distribu- tions, were recomputed using an in-house fast Monte Carlo dose calculator with a FRBE of 1.1 or with a previously published VRBE model. We then compared dosimetric parameters obtained by the VRBE with those obtained by the FRBE. Biological doses obtained by the VRBE for the clinical target volume in all plans were 1% - 2% larger than those obtained by the FRBE. The minimum dose obtained by the VRBE for the right optic nerve in the MFO IMPT with 4 fields was 70% larger than that obtained by the FRBE, but the difference was only 18.1 cGy (RBE). The difference in maximum dose for the right optic nerve in the MFO IMPT with 5 fields was less than 10.4%, but the difference was 131.8 cGy (RBE). The mean difference in maximum dose was less than 2% for all other organs at risk. We found that biological dose with the FRBE had any dose errors in IMPT with various multi-angle beams. | |||||
書誌情報 |
International Journal of Medical Physics, Clinical Engineering and Radiation Oncology 巻 8, p. 32-45, 発行日 2019-02 |
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出版者 | ||||||
出版者 | Scientific Research Publishing | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 2168-5444 | |||||
DOI | ||||||
識別子タイプ | DOI | |||||
関連識別子 | 10.4236/ijmpcero.2019.81004 | |||||
関連サイト | ||||||
識別子タイプ | URI | |||||
関連識別子 | https://www.scirp.org/journal/PaperInformation.aspx?PaperID=90414 |