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In-field and out-of-file application in 12C ion therapy using fully 3D silicon microdosimeters
https://repo.qst.go.jp/records/74857
https://repo.qst.go.jp/records/748579f99ae60-f764-4754-b09c-675789e59c55
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2019-03-19 | |||||
| タイトル | ||||||
| タイトル | In-field and out-of-file application in 12C ion therapy using fully 3D silicon microdosimeters | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
T. Tran, Linh
× T. Tran, Linh× Chartier, Lachlan× Bolst, David× Jeremy, Davis× A.Prokopovich, Dale× Pogossov, Alex× Guatelli, Susanna× I. Reinhard, Mark× Petasecca, Marco× L.F. Lerch, Michael× 松藤, 成弘× Pavoli, Marco× Summanwar, Anand× Kok, Angela× Jackson, Michael× B. Rosenfeld, Anatoly× Linh Tran, Thuy× Lachlan, Chartier× BOLST, David× Davis, Jeremy× Prokopovich, Dale× Petasecca, Marco× Lerch, Michael× Matsufuji, Naruhiro× Anatoly, Rozenfeld |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | This paper presents recent development of Silicon on Insulator (SOI) detectors for microdosimetry at the Centre for Medical Radiation Physics (CMRP) at the University of Wollongong. A new CMRP SOI microdosimeter design, the 3D mushroom microdosimeter is presented. Modification of SOI design and changes to the fabrication processes have led to improved definition of the microscopic sensitive volumes (SV), and thus to better modelling of the deposition of ionizing energy in a biological cell. The electrical and charge collection properties of the devices have been presented in previous works. In this study, the response of the microdosimeters in monoenergetic and spread out Bragg peak therapeutic 12C ion beam at Heavy Ion Medical Accelerator in Chiba (HIMAC, Japan) are presented. Derived relative biological effectiveness (RBE) in 12C ion radiation therapy matches the tissue equivalent proportional counter (TEPC) well, along with outstanding spatial resolution. The use of SOI technology in experimental microdosimetry offers simplicity (no gas system or HV supply), high spatial resolution, low cost, high count rates capabilities for beam characterisation and quality assurance (QA) in charged particle therapy. | |||||
| 書誌情報 |
Radiation Measurements 巻 115, p. 55-59, 発行日 2019-03 |
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| 出版者 | ||||||
| 出版者 | Elsevier | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 1350-4487 | |||||
| DOI | ||||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.1016/j.radmeas.2018.06.015 | |||||
| 関連サイト | ||||||
| 識別子タイプ | URI | |||||
| 関連識別子 | https://www.sciencedirect.com/science/article/pii/S1350448718301355 | |||||
