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Rapid detection of uranium in blood extracted from wounds using X-ray fluorescence analysis
https://repo.qst.go.jp/records/74820
https://repo.qst.go.jp/records/7482005355b84-6ee7-4af4-9f77-8039d30d8314
| Item type | 会議発表用資料 / Presentation(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2019-03-19 | |||||
| タイトル | ||||||
| タイトル | Rapid detection of uranium in blood extracted from wounds using X-ray fluorescence analysis | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_c94f | |||||
| 資源タイプ | conference object | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Izumoto, Yukie
× Izumoto, Yukie× Matsuyama, Tsugufumi× Ishii, Kota× Sakai, Yasuhiro× Oguri, Yoshiyuki× Yoshii, Hiroshi× Izumoto, Yukie× Matsuyama, Tsugufumi× Ishii, Kota× Yoshii, Hiroshi |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Workers in nuclear handling facilities have a finite risk of injury and contamination in wounds from uranium. Due to their hazardous nature, accidental intake of uranium such as from wounds can lead to a considerable amount of internal exposure. Although an appropriate surgical resection of tissue in the contaminated wound is useful to suppress the additional intake of uranium, rapid quantification of uranium in the wound is required to avoid unnecessary surgeries. For surface contaminations, the rapid detection of uranium is usually performed via the -particle counting method. However, in case of wound contamination, most of the -particles emitted from uranium cannot pass through the oozing blood from the wound. Therefore, X-ray fluorescence (XRF) analysis can be an alternative approach to the detection of uranium because X-rays can pass through several millimeters of blood or soft tissue. In this study, we developed a new methodology for the rapid detection of uranium in wounds based on X-ray fluorescence analysis of contaminated blood collected by filter paper. Mouse blood contaminated with uranyl acetate solutions having different concentrations were dropped on the filter paper and were subjected to XRF using a desktop XRF device (SEA1100 Hitachi High-Tech Science). The X-ray tube voltage was 50 kV, and the tube current was 1 mA. The X-ray accumulation time was 60 sec. Since the obtained U Lα (13.6 keV) peak from the XRF analysis was overlapping with the Rb Kα (13.4 keV) and Br Kβ (13.3 keV) peaks (Figure 1), a Gaussian fitting was performed in order to separate them. Up to 25 ppm, the net count of the U Lα peak was directly proportional to the uranium concentration, and the obtained detection limit was low enough to detect uranium in emergency situations. These results confirm that the XRF approach is useful for the rapid detection of uranium in oozing wounds at radiation emergency medical facilities. |
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| 会議概要（会議名, 開催地, 会期, 主催者等） | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | European Conference on X-ray Spectrometry (EXRS2018) | |||||
| 発表年月日 | ||||||
| 日付 | 2018-07-23 | |||||
| 日付タイプ | Issued | |||||
