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How Do We Establish Cardiac Sympathetic Nervous System Imaging with 123I-mIBG in Clinical Practice? Perspectives and Lessons from Japan and the US
https://repo.qst.go.jp/records/73845
https://repo.qst.go.jp/records/738459a895f8c-c0af-4886-a401-1fe1f7c2e936
Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2018-09-07 | |||||
タイトル | ||||||
タイトル | How Do We Establish Cardiac Sympathetic Nervous System Imaging with 123I-mIBG in Clinical Practice? Perspectives and Lessons from Japan and the US | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
アクセス権 | ||||||
アクセス権 | metadata only access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
著者 |
I.Travin, Mark
× I.Travin, Mark× Matsunari, Ichiro× S. Thomas, Gregory× Nakajima, Kenichi× Yoshinaga, Keiichiro× Yoshinaga, Keiichiro |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Cardiac denervation is associated with progressive left ventricular (LV) dysfunction, ventricular arrhythmias, and sudden cardiac death (SCD) in heart failure (HF). In this regard, it is important to evaluate cardiac-specific sympathetic nervous system (SNS) function. The radiotracer Iodine-123 meta-iodobenzylguanidine (123I-mIBG) can noninvasively evaluate pre-synaptic SNS function. Recent multicenter trials have shown 123I-mIBG to have strong predictive value for fatal arrhythmias and cardiac death in HF. 123I-mIBG was initially developed in the USA in the 1970s. In 1992, the Japanese Ministry of Health and Labour approved 123I-mIBG for the assessment of cardiac function. Following approval, the Japanese nuclear cardiology community developed 123I-mIBG imaging services in various medical centers. Japanese groups have been trying to establish the clinical utility of 123I-mIBG and standardize parameters for data acquisition and image analysis. The US Food and Drug Administration (FDA) has approved clinical use of 123I-mIBG for cardiac and non-cardiac imaging. However, clinical use of 123I-mIBG in the US has been very limited. The number of 123I-mIBG studies in Japan has also been limited. There are similarities and differences between the two countries. To establish the clinical utility of 123I-mIBG in both countries, it is important to characterize the situations of 123I-mIBG in each. | |||||
書誌情報 |
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology 巻 26, 号 4, p. 1434-1451, 発行日 2018-08 |
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出版者 | ||||||
出版者 | Springer | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 1071-3581 | |||||
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識別子タイプ | PMID | |||||
関連識別子 | 30178272 | |||||
DOI | ||||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1007/s12350-018-1394-5 | |||||
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識別子タイプ | URI | |||||
関連識別子 | https://link.springer.com/article/10.1007/s12350-018-1394-5 |