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  1. 原著論文

How Do We Establish Cardiac Sympathetic Nervous System Imaging with 123I-mIBG in Clinical Practice? Perspectives and Lessons from Japan and the US

https://repo.qst.go.jp/records/73845
https://repo.qst.go.jp/records/73845
9a895f8c-c0af-4886-a401-1fe1f7c2e936
Item type 学術雑誌論文 / Journal Article(1)
公開日 2018-09-07
タイトル
タイトル How Do We Establish Cardiac Sympathetic Nervous System Imaging with 123I-mIBG in Clinical Practice? Perspectives and Lessons from Japan and the US
言語
言語 eng
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ journal article
アクセス権
アクセス権 metadata only access
アクセス権URI http://purl.org/coar/access_right/c_14cb
著者 I.Travin, Mark

× I.Travin, Mark

WEKO 804366

I.Travin, Mark

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Matsunari, Ichiro

× Matsunari, Ichiro

WEKO 804367

Matsunari, Ichiro

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S. Thomas, Gregory

× S. Thomas, Gregory

WEKO 804368

S. Thomas, Gregory

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Nakajima, Kenichi

× Nakajima, Kenichi

WEKO 804369

Nakajima, Kenichi

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Yoshinaga, Keiichiro

× Yoshinaga, Keiichiro

WEKO 804370

Yoshinaga, Keiichiro

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Yoshinaga, Keiichiro

× Yoshinaga, Keiichiro

WEKO 804371

en Yoshinaga, Keiichiro

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抄録
内容記述タイプ Abstract
内容記述 Cardiac denervation is associated with progressive left ventricular (LV) dysfunction, ventricular arrhythmias, and sudden cardiac death (SCD) in heart failure (HF). In this regard, it is important to evaluate cardiac-specific sympathetic nervous system (SNS) function. The radiotracer Iodine-123 meta-iodobenzylguanidine (123I-mIBG) can noninvasively evaluate pre-synaptic SNS function. Recent multicenter trials have shown 123I-mIBG to have strong predictive value for fatal arrhythmias and cardiac death in HF. 123I-mIBG was initially developed in the USA in the 1970s. In 1992, the Japanese Ministry of Health and Labour approved 123I-mIBG for the assessment of cardiac function. Following approval, the Japanese nuclear cardiology community developed 123I-mIBG imaging services in various medical centers. Japanese groups have been trying to establish the clinical utility of 123I-mIBG and standardize parameters for data acquisition and image analysis. The US Food and Drug Administration (FDA) has approved clinical use of 123I-mIBG for cardiac and non-cardiac imaging. However, clinical use of 123I-mIBG in the US has been very limited. The number of 123I-mIBG studies in Japan has also been limited. There are similarities and differences between the two countries. To establish the clinical utility of 123I-mIBG in both countries, it is important to characterize the situations of 123I-mIBG in each.
書誌情報 Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology

巻 26, 号 4, p. 1434-1451, 発行日 2018-08
出版者
出版者 Springer
ISSN
収録物識別子タイプ ISSN
収録物識別子 1071-3581
PubMed番号
識別子タイプ PMID
関連識別子 30178272
DOI
識別子タイプ DOI
関連識別子 10.1007/s12350-018-1394-5
関連サイト
識別子タイプ URI
関連識別子 https://link.springer.com/article/10.1007/s12350-018-1394-5
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