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Cortical processing of others' action in the STS of common marmoset revealed by optical intrinsic signal imaging
https://repo.qst.go.jp/records/73126
https://repo.qst.go.jp/records/7312618d3c370-9107-4c07-ac39-cc5c8f57a3dc
| Item type | 会議発表用資料 / Presentation(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2018-12-28 | |||||
| タイトル | ||||||
| タイトル | Cortical processing of others' action in the STS of common marmoset revealed by optical intrinsic signal imaging | |||||
| 言語 | ||||||
| 言語 | jpn | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_c94f | |||||
| 資源タイプ | conference object | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
鈴木, 航
× 鈴木, 航× 谷, 利樹× 速水, 琢× 坂野, 拓× 宮川, 尚久× 阿部, 央× 渡邉, 恵× 益子, 宏美× 一戸, 紀孝× 宮川 尚久 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Superior temporal sulcus (STS) of human and Old World monkey contains multiple-cortical areas that are recognized as input regions to social brain network. Functional roleof each individual area in STS, however, is not well understood, because complex shape of the sulcus makes it difficult to identify each area, especially under in vivo condition. A small New World monkey, the common marmoset (Callithrix jacchus) has a lissencephalic and small brain with visual cortical areas comparable to those of the macaque monkey, and, thus, is adequate animal model to investigate the information processing along their multiple-areas in STS. In the present study, we visualized multiple-cortical areas in STS using optical intrinsic signal imaging (OISI) and investigated the response properties of each area to stimuli with different levels of complexity: flashing and moving random dots, and movies of goal directed behavior of a marmoset. By conducting craniotomy and duratomy on the temporal lobe of anesthetized marmosets, a large cortical region around STS was exposed, and a band-passed light with 535nm center wavelength was illuminated on the cortical surface. Visual stimuli were presented to the anesthetized marmoset while the backscattered light was detected by CCD camera. Changes in backscattered light following a stimulus onset were defined as functional optical signals evoked by the visual stimulus. First, we extracted areas with retinotopic organization using the flashing random dots presented in annulus or wedge shapes in the visual field. Spatial distribution of the optical signals in areas MT and MTc followed the retinotopic organization reported in the previous studies. Areas anterior to the areas MT and MTc were not responsive to the flashing random dots. Using optic flow stimuli with moving random dots, we further identified motion selective regions including area MT and MTc. The movies of the other's grasping a food elicited optical signals not only in the motion selective regions, but also in area FST which was not sensitive to optical flow stimuli. In addition, the movies of other marmoset grasping vacant target significantly reduced the optical signals in the responsive regions, especially in late phase of the signals. These results suggest that multiple-areas in STS play different levels of functional roles for representing the other's social behavior and would even represent a goal of the others' action. | |||||
| 会議概要（会議名, 開催地, 会期, 主催者等） | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | 第41回日本神経科学大会 | |||||
| 発表年月日 | ||||||
| 日付 | 2018-07-28 | |||||
| 日付タイプ | Issued | |||||
