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Small lesion imaging performance of a novel helmet-neck PET prototype: a phantom study
https://repo.qst.go.jp/records/72675
https://repo.qst.go.jp/records/726758415651c-c9bb-4f07-93b6-054704827003
| Item type | 会議発表用資料 / Presentation(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2018-03-05 | |||||
| タイトル | ||||||
| タイトル | Small lesion imaging performance of a novel helmet-neck PET prototype: a phantom study | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_c94f | |||||
| 資源タイプ | conference object | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Akamatsu, Go
× Akamatsu, Go× Tashima, Hideaki× Iwao, Yuma× Wakizaka, Hidekatsu× Maeda, Takamasa× Yoshida, Eiji× Yamashita, Taichi× Yamaya, Taiga× 赤松 剛× 田島 英朗× 岩男 悠真× 脇坂 秀克× 前田 貴雅× 吉田 英治× 山下 大地× 山谷 泰賀 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Objectives: Brain PET imaging is frequently used in clinical practice and research. A high lesion detectability is required in neuro-oncology field because the brain tumor extent is clinically relevant. Therefore, we have developed a brain-dedicated high-resolution and high-sensitivity PET prototype. In this study, we evaluated the small lesion imaging performance of the brain PET prototype using a small sphere phantom. Materials and methods: The helmet-neck PET is our original brain PET system, in which 47 four-layer depth-of-interaction detectors are used to form a hemisphere and 7 of them are placed on the neck part. The phantom had six small spheres (Inner diameters: 22, 17, 13, 10, 8, and 5 mm), which were filled with three times higher radioactivity concentration of the background. The background radioactivity was 1.32kBq/mL, which was generally half radioactivity level compared with clinical neuro-oncology PET. PET data were acquired for 20-min and were reconstructed with ordered-subsets expectation-maximization algorithm. The %contrast in each sphere and coefficient-of-variation on the background area (CVBG) were calculated to evaluate lesion detectability and image quality. Results: On the images reconstructed with 8-iterations and 8-subsets, the 8-mm-sphere was clearly observed. The %contrast of the 8-mm-sphere was 35.8% and the CVBG was 16.0%. The %contrast obviously achieved the criteria described by the previous report (%contrast >13%). Conclusion: The novel helmet-neck PET showed great small lesion detectability even though the radioactivity level was a lower condition. Therefore, the helmet-neck PET has a potential to not only improve small lesion detectability but also reduce injection activity or scanning duration. |
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| 会議概要（会議名, 開催地, 会期, 主催者等） | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | ECR2018 | |||||
| 発表年月日 | ||||||
| 日付 | 2018-02-28 | |||||
| 日付タイプ | Issued | |||||
