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Small lesion imaging performance of a novel helmet-neck PET prototype: a phantom study

https://repo.qst.go.jp/records/72675
https://repo.qst.go.jp/records/72675
8415651c-c9bb-4f07-93b6-054704827003
Item type 会議発表用資料 / Presentation(1)
公開日 2018-03-05
タイトル
タイトル Small lesion imaging performance of a novel helmet-neck PET prototype: a phantom study
言語
言語 eng
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_c94f
資源タイプ conference object
アクセス権
アクセス権 metadata only access
アクセス権URI http://purl.org/coar/access_right/c_14cb
著者 Akamatsu, Go

× Akamatsu, Go

WEKO 715756

Akamatsu, Go

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Tashima, Hideaki

× Tashima, Hideaki

WEKO 715757

Tashima, Hideaki

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Iwao, Yuma

× Iwao, Yuma

WEKO 715758

Iwao, Yuma

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Wakizaka, Hidekatsu

× Wakizaka, Hidekatsu

WEKO 715759

Wakizaka, Hidekatsu

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Maeda, Takamasa

× Maeda, Takamasa

WEKO 715760

Maeda, Takamasa

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Yoshida, Eiji

× Yoshida, Eiji

WEKO 715761

Yoshida, Eiji

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Yamashita, Taichi

× Yamashita, Taichi

WEKO 715762

Yamashita, Taichi

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Yamaya, Taiga

× Yamaya, Taiga

WEKO 715763

Yamaya, Taiga

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赤松 剛

× 赤松 剛

WEKO 715764

en 赤松 剛

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田島 英朗

× 田島 英朗

WEKO 715765

en 田島 英朗

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岩男 悠真

× 岩男 悠真

WEKO 715766

en 岩男 悠真

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脇坂 秀克

× 脇坂 秀克

WEKO 715767

en 脇坂 秀克

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前田 貴雅

× 前田 貴雅

WEKO 715768

en 前田 貴雅

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吉田 英治

× 吉田 英治

WEKO 715769

en 吉田 英治

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山下 大地

× 山下 大地

WEKO 715770

en 山下 大地

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山谷 泰賀

× 山谷 泰賀

WEKO 715771

en 山谷 泰賀

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抄録
内容記述タイプ Abstract
内容記述 Objectives: Brain PET imaging is frequently used in clinical practice and research. A high lesion detectability is required in neuro-oncology field because the brain tumor extent is clinically relevant. Therefore, we have developed a brain-dedicated high-resolution and high-sensitivity PET prototype. In this study, we evaluated the small lesion imaging performance of the brain PET prototype using a small sphere phantom.
Materials and methods: The helmet-neck PET is our original brain PET system, in which 47 four-layer depth-of-interaction detectors are used to form a hemisphere and 7 of them are placed on the neck part. The phantom had six small spheres (Inner diameters: 22, 17, 13, 10, 8, and 5 mm), which were filled with three times higher radioactivity concentration of the background. The background radioactivity was 1.32kBq/mL, which was generally half radioactivity level compared with clinical neuro-oncology PET. PET data were acquired for 20-min and were reconstructed with ordered-subsets expectation-maximization algorithm. The %contrast in each sphere and coefficient-of-variation on the background area (CVBG) were calculated to evaluate lesion detectability and image quality.
Results: On the images reconstructed with 8-iterations and 8-subsets, the 8-mm-sphere was clearly observed. The %contrast of the 8-mm-sphere was 35.8% and the CVBG was 16.0%. The %contrast obviously achieved the criteria described by the previous report (%contrast >13%).
Conclusion: The novel helmet-neck PET showed great small lesion detectability even though the radioactivity level was a lower condition. Therefore, the helmet-neck PET has a potential to not only improve small lesion detectability but also reduce injection activity or scanning duration.
会議概要(会議名, 開催地, 会期, 主催者等)
内容記述タイプ Other
内容記述 ECR2018
発表年月日
日付 2018-02-28
日付タイプ Issued
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