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DNA conformational transition inferred from re-evaluation of m|Fo|-D|Fc| electron density maps
https://repo.qst.go.jp/records/72083
https://repo.qst.go.jp/records/720832b5122e3-b9b2-4ebc-99f3-18f6b190b416
| Item type | 会議発表用資料 / Presentation(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2016-12-07 | |||||
| タイトル | ||||||
| タイトル | DNA conformational transition inferred from re-evaluation of m|Fo|-D|Fc| electron density maps | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_c94f | |||||
| 資源タイプ | conference object | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
角南, 智子
× 角南, 智子× 河野, 秀俊× 角南 智子× 河野 秀俊 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Flexibility of DNA plays important roles on biological processes. Recent analyses have indicated that traditional refinement does not always give us accurate crystallographic heterogeneity and some information of DNA flexibility is possibly overlooked in previous crystallographic studies. We re-calculated m|Fo|-D|Fc| electron density maps of double helical DNA crystal structures in PDB to utilize the overlooked information. We observed potential conformational transitions in 27% of DNA phosphates analyzed. The present results indicate that peaks around phosphates in the m|Fo|-D|Fc| maps of Z-DNA and B-DNA sometimes corresponds to ZI ZII and A/B -> BI transitions, respectively. We also discuss effect of metal-coordination on conformational transitions in Z-DNA. | |||||
| 会議概要（会議名, 開催地, 会期, 主催者等） | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | 第54回日本生物物理学会年会に参加。 | |||||
| 発表年月日 | ||||||
| 日付 | 2016-11-25 | |||||
| 日付タイプ | Issued | |||||
