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Decomposition of averaged EM images by 2D hybrid analysis
https://repo.qst.go.jp/records/72077
https://repo.qst.go.jp/records/72077393053bf-88f4-4f89-9a60-bc97cd38563b
| Item type | 会議発表用資料 / Presentation(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2016-11-29 | |||||
| タイトル | ||||||
| タイトル | Decomposition of averaged EM images by 2D hybrid analysis | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_c94f | |||||
| 資源タイプ | conference object | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
松本, 淳
× 松本, 淳× 松本 淳 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | We are developing a computational approach (2D hybrid analysis) to build a 3D atomic model from an electron microscope (EM) image of a biological molecule. In this approach, firstly a lot of atomic models are built by deforming the X-ray crystal structure (or the modeled structure). Then, the projections of each model are created. Finally, they are compared with the EM image to select the best-fitting atomic model. We have recently introduced the realistic projection model (the negative stain model) to improve the accuracy of the computation. This has enabled us to decompose the averaged EM images. In principle, averaging of EM images should be performed using the raw images of molecules with the same conformation and orientation. Actually, mixture occurs. Now we can detect such mixture by the 2D hybrid analysis. |
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| 会議概要（会議名, 開催地, 会期, 主催者等） | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | 第54回日本生物物理学会年会に参加。 | |||||
| 発表年月日 | ||||||
| 日付 | 2016-11-27 | |||||
| 日付タイプ | Issued | |||||
