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Cell cycle-correlative bystander effects are co-mediated by DNA-PKcs and ATM kinase after high LET carbon ions irradiation
https://repo.qst.go.jp/records/71645
https://repo.qst.go.jp/records/716457e0346d5-213d-47ac-b0e1-2c2d395ee4b8
Item type | 会議発表用資料 / Presentation(1) | |||||
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公開日 | 2015-04-28 | |||||
タイトル | ||||||
タイトル | Cell cycle-correlative bystander effects are co-mediated by DNA-PKcs and ATM kinase after high LET carbon ions irradiation | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_c94f | |||||
資源タイプ | conference object | |||||
アクセス権 | ||||||
アクセス権 | metadata only access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
著者 |
Tu, Wenzhi
× Tu, Wenzhi× Dong, Chen× Konishi, Teruaki× Kobayashi, Alisa× Furusawa, Yoshiya× Uchihori, Yukio× Shao, Chunlin× 小西 輝昭× 小林 亜利紗× 古澤 佳也× 内堀 幸夫 |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Radiation-induced bystander effects (RIBE) was demonstrated with accumulated evidence. Recently, several studies have focused on the role of DNA damage and repair in the bystander response, but the heavy ions induced, especially cell cycle-correlative RIBE are still largely unclear. Our present study found that G2/M phase cells had the largest contribution to the RIBE induced by carbon ions irradiation and identified a pivotal role for DNA-PKcs and ATM in this process as two independent factors. | |||||
会議概要(会議名, 開催地, 会期, 主催者等) | ||||||
内容記述タイプ | Other | |||||
内容記述 | 平成26年度放射線医学総合研究所重粒子線がん治療装置等共同利用研究報告会 | |||||
発表年月日 | ||||||
日付 | 2015-04-20 | |||||
日付タイプ | Issued |