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The Effect of dose-delivery time structure on biological effectiveness for charged particle therapy

https://repo.qst.go.jp/records/71385
https://repo.qst.go.jp/records/71385
ec1a214e-17aa-47bc-9e7a-1a1f3015438b
Item type 会議発表用資料 / Presentation(1)
公開日 2013-12-04
タイトル
タイトル The Effect of dose-delivery time structure on biological effectiveness for charged particle therapy
言語
言語 eng
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_c94f
資源タイプ conference object
アクセス権
アクセス権 metadata only access
アクセス権URI http://purl.org/coar/access_right/c_14cb
著者 Inaniwa, Taku

× Inaniwa, Taku

WEKO 701881

Inaniwa, Taku

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Suzuki, Masao

× Suzuki, Masao

WEKO 701882

Suzuki, Masao

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Furukawa, Takuji

× Furukawa, Takuji

WEKO 701883

Furukawa, Takuji

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Mori, Shinichiro

× Mori, Shinichiro

WEKO 701884

Mori, Shinichiro

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Kanematsu, Nobuyuki

× Kanematsu, Nobuyuki

WEKO 701885

Kanematsu, Nobuyuki

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Shirai, Toshiyuki

× Shirai, Toshiyuki

WEKO 701886

Shirai, Toshiyuki

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et.al

× et.al

WEKO 701887

et.al

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稲庭 拓

× 稲庭 拓

WEKO 701888

en 稲庭 拓

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鈴木 雅雄

× 鈴木 雅雄

WEKO 701889

en 鈴木 雅雄

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古川 卓司

× 古川 卓司

WEKO 701890

en 古川 卓司

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森 慎一郎

× 森 慎一郎

WEKO 701891

en 森 慎一郎

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兼松 伸幸

× 兼松 伸幸

WEKO 701892

en 兼松 伸幸

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白井 敏之

× 白井 敏之

WEKO 701893

en 白井 敏之

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抄録
内容記述タイプ Abstract
内容記述 Treatment plans of c-ion radiotherapy have been made on the assumption that the beams in one fraction are delivered instantaneously by neglecting the dose delivery time as well as the interruption time. However, in practical treatments, it takes 1-10 minutes or longer to deliver a fractional dose to a patient depending on the prescribed dose level, the dose delivery technique and the performance of the delivery system. Especially, the advanced therapeutic techniques such as a hypo-fractionation and a respiratory gating usually require more time to deliver a fractional dose than the convetional one. In addition, the dose delivery can be interrupted due to some reasons such as the necessity of a patient re-setup between fields in a treatment fraction and machine troubles. Cell killing tends to decrease with the fraction time because of sublethal damage repair (SLDR). Thus, it is important to investigate the quantity of SLDR during the fraction time and to evaluate the effects of dose-delivery time structure on the biological effectiveness of therapeutic c-ion beams. In this study, the Microdosimetric Kinetic Model (MKM) was adopted to address this issue.
会議概要(会議名, 開催地, 会期, 主催者等)
内容記述タイプ Other
内容記述 4D Treatment planning workshop 2013
発表年月日
日付 2013-11-29
日付タイプ Issued
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