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A MRI-Based PET Attenuation Correction with mu-Values Measured by a Fixed-Position Radiation Source
https://repo.qst.go.jp/records/71322
https://repo.qst.go.jp/records/713228ce01744-967c-4c2c-8936-f8cf2c7e794e
| Item type | 会議発表用資料 / Presentation(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2013-11-06 | |||||
| タイトル | ||||||
| タイトル | A MRI-Based PET Attenuation Correction with mu-Values Measured by a Fixed-Position Radiation Source | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_c94f | |||||
| 資源タイプ | conference object | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Kawaguchi, Hiroshi
× Kawaguchi, Hiroshi× Hirano, Yoshiyuki× Yoshida, Eiji× Suga, Mikio× Shiraishi, Takahiro× Tanimoto, Katsuyuki× Kimura, Yasuyuki× Obata, Takayuki× Ito, Hiroshi× Yamaya, Taiga× 川口 拓之× 平野 祥之× 吉田 英治× 菅 幹生× 白石 貴博× 谷本 克之× 木村 泰之× 小畠 隆行× 伊藤 浩× 山谷 泰賀 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Several MRI-based attenuation correction methods have been reported for PET/MRI. The accuracy of the attenuation map (mu-map) from an MRI image depends on correctness of the segmentation of tissue and the attenuation coefficients to be assigned (mu-values). However, an MRI image does not reflect the attenuation of radiation and inaccurate assignment of mu-values affects the quantitative assessment of functional images of PET. Although installation of a transmission scan function on the PET/MRI can provide an accurate mu-map, it restricts the design of the scanner, increases the manufacturing cost and takes additional scanning time. In this study, we proposed an MRI-based mu-value estimation method with a non-rotational radiation source to construct the proper mu-map for PET/MRI. The proposed method uses the accurately segmented tissue map, the partial path length of each tissue, and detected intensities of attenuated radiation from a fixed-position radiation source which usually rotates around the subject to obtain the mu-map with the tomographic procedure. According to the Lambert-Beer law, attenuated intensity is described as the function of partial path length and mu-values of every tissue. The partial path length could be estimated by the simulation of fixed-point radiation with the same scanner geometry using the known tissue map from MRI. The mu-values of every tissue could be estimated by inverting the function. The simulation results, based upon measurement data, showed the averaged errors between mu-values of the conventional transmission scan and our proposed method were 2.3%, 18.6% and -11.1% for brain, bone and soft tissue other than brain, respectively. Although there were over- and under-estimations for bone and soft tissue, respectively, the present method is able to estimate the brain mu-value accurately and that strongly affects the quantitative value of PET images because of the large volumetric ratio of the brain. | |||||
| 会議概要（会議名, 開催地, 会期, 主催者等） | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | IEEE NSS/MIC/RTSD 2013 | |||||
| 発表年月日 | ||||||
| 日付 | 2013-11-02 | |||||
| 日付タイプ | Issued | |||||
