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Carbonion Scanning Lung Therapy (with Respiratory-gated Phase Controlled Rescanning): Simulation Study for 4D Treatment Planning
https://repo.qst.go.jp/records/71269
https://repo.qst.go.jp/records/712692524675e-e17f-4aff-adee-17927d99f5ad
| Item type | 会議発表用資料 / Presentation(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2013-09-30 | |||||
| タイトル | ||||||
| タイトル | Carbonion Scanning Lung Therapy (with Respiratory-gated Phase Controlled Rescanning): Simulation Study for 4D Treatment Planning | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_c94f | |||||
| 資源タイプ | conference object | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Takahashi, Wataru
× Takahashi, Wataru× Mori, Shinichiro× Furukawa, Takuji× Inaniwa, Taku× Nakajima, Mio× Shirai, Toshiyuki× Noda, Kouji× Yamamoto, Naoyoshi× Kamada, Tadashi× 高橋 渉× 森 慎一郎× 古川 卓司× 稲庭 拓× 中嶋 美緒× 白井 敏之× 野田 耕司× 山本 直敬× 鎌田 正 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Purpose/Objective(s) To provide mostly satisfactory dose conformity to the moving target, we applied a respiratorygated strategy to the carbonion active scanning lung treatment with multiple phase controlled rescannings (PCR). Here, we quantified the dose assessment using 4DCT data set. Materials/Methods Total 14 patients with lung tumor (stage I nonsmallcell lung cancer or oligometastatic lung tumor) were randomly selected. Volumetric cine CT images were acquired in 4D mode under free breathing conditions. Pencilbeam scanning carbonion radiotherapy (PBSCIRT) plans were created for each patient. The gross tumor volume, the clinical target volume (CTV) and organ at risks (OARs) were delineated. Fieldspecific target volumes (FTVs) were calculated for respective beam fields two types of FTVs were designed for ungated (full respiratory cycle) and gated (T40T60) strategies. The prescribed dose of 48Gy(RBE) in single fraction was given to the FTVs with different coplanar four angles. As technique of irradiation for moving target, two methods were used in current study (1) respiratory gating for motion mitigation, (2) PCR to obtain a conformal dose distribution. We evaluated the dose metrics by changing the number of PCRs and compared them in between ungated and gated strategies. To calculate the accumulated dose distribution, the deformable image registration was applied to transfer dose distributions at respective phases to the reference phase. Results By defining of FTV, undershooting to the target could be generally avoided in each respiratory phase. As shown in Table, D95 of the treatment dose was 94.4+-1.9% even in 1x PCR ungated plan. In gating plan, significant improvements in all the dose volume indices of CTV and OARs were found compared with ungated plan. Moreover, observe that the CTV coverage improved gradually as the number of PCR increased. 4 times or more of PCR resulted in adequate target coverage. As for OARs, the dose indices of lung V20, Dmax of heart and spinal cord did not change significantly according to increasing PCR. These metrics were improved only with respiratory gating. For instance, dose to lung V20 was decreased 12% (4.3Gy(RBE) in ungated plan to 3.8Gy(RBE) in gated). Conclusions For a moving target, PBSCIRT system with gating and PCR accurately achieve homogenous dose distribution even in actual patients. |
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| 会議概要（会議名, 開催地, 会期, 主催者等） | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | ASTRO's 55th Annual Meeting | |||||
| 発表年月日 | ||||||
| 日付 | 2013-09-25 | |||||
| 日付タイプ | Issued | |||||
