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Factors related to positive PET findings in patients with high CEA levels.
https://repo.qst.go.jp/records/71229
https://repo.qst.go.jp/records/712292ecbdb89-2c9a-4c67-bdd3-d07126a2589b
| Item type | 会議発表用資料 / Presentation(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2013-09-03 | |||||
| タイトル | ||||||
| タイトル | Factors related to positive PET findings in patients with high CEA levels. | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_c94f | |||||
| 資源タイプ | conference object | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Suga, Tsuyoshi
× Suga, Tsuyoshi× Nakamoto, Yuji× Higashi, Tatsuya× Saga, Tsuneo× Hara, Tadashi× Togashi, Kaori× et.al× 佐賀 恒夫 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Objectives: Rising carcinoembryonic antigen (CEA), one of the popular tumor markers, is a common situation for requesting FDG-PET. However, details remain unknown about the correlation of the FDG-PET findings and the patients status. The purpose of this study was to evaluate the factors related to positive PET results in patients with high serum CEA levels. Methods: From January 2005 to December 2005, a total of 282 patients with high serum CEA levels (>5.0 ng/ml) underwent an FDG-PET scan in our institute. Of these 282 patients, 19 patients had repeated PET scans, After excluding repeated 22 scans in those patients, 260 scans were analyzed in this study. The PET findings were correlated with clinical information, including the presence or absence of a previous history of malignancy, an increase or decrease in CEA level before PET, and the absolute value of the serum CEA level. Results: Overall, abnormal foci were detected in 167 of 260 patients (64%) by FDG-PET in this study. Among the 260 patients, 208 patients had a history of previous malignancy. The PET findings were positive in 136 of these 208 patients (65%), while they were positive in 31 of 52 patients (60%) without a history of malignancy. The difference was not statistically significant (p=0.54). For 154 patients who had serial CEA tests before a PET scan, positive results were obtained in 60 of 107 patients (62%) who showed an increasing pattern of CEA level, and in 16 of 47 patients (34%) with a decreasing pattern, which was statistically significant (p<0.01). The prevalence of PET positive cases increased with the increase in CEA level. When the CEA level was greater than 12 ng/ml, PET revealed positive results in more than 80% of the patients. Conclusions: Our preliminary data suggest that a high level of CEA and increasing pattern of CEA correlated with positive PET findings. Patients with high CEA level, especially accompanied by increasing pattern, would be justified to undergo FDG-PET scan for determining therapeutic management. The prevalence of PET positive cases. CEA (ng/ml): 5-10, 10-25, 25-50, >50 # of total cases: 138, 62, 23, 37 # of positive cases: 73(53%), 43(69%), 19(83%), 32(86%) |
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| 会議概要（会議名, 開催地, 会期, 主催者等） | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | Society of nuclear medicine 54rd Annual Meetng | |||||
| 発表年月日 | ||||||
| 日付 | 2007-06-06 | |||||
| 日付タイプ | Issued | |||||
