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Evaluation of Inter-Scanner Differences in Effect of Radioactivity from Outside FOV

https://repo.qst.go.jp/records/70850
https://repo.qst.go.jp/records/70850
d78e1495-975d-46cc-aa5e-05cbcfd43532
Item type 会議発表用資料 / Presentation(1)
公開日 2012-08-17
タイトル
タイトル Evaluation of Inter-Scanner Differences in Effect of Radioactivity from Outside FOV
言語
言語 eng
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_c94f
資源タイプ conference object
アクセス権
アクセス権 metadata only access
アクセス権URI http://purl.org/coar/access_right/c_14cb
著者 Shiraishi, Takahiro

× Shiraishi, Takahiro

WEKO 696194

Shiraishi, Takahiro

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Kimura, Yasuyuki

× Kimura, Yasuyuki

WEKO 696195

Kimura, Yasuyuki

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Kanno, Iwao

× Kanno, Iwao

WEKO 696196

Kanno, Iwao

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Suhara, Tetsuya

× Suhara, Tetsuya

WEKO 696197

Suhara, Tetsuya

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Ito, Hiroshi

× Ito, Hiroshi

WEKO 696198

Ito, Hiroshi

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白石 貴博

× 白石 貴博

WEKO 696199

en 白石 貴博

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木村 泰之

× 木村 泰之

WEKO 696200

en 木村 泰之

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菅野 巖

× 菅野 巖

WEKO 696201

en 菅野 巖

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須原 哲也

× 須原 哲也

WEKO 696202

en 須原 哲也

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伊藤 浩

× 伊藤 浩

WEKO 696203

en 伊藤 浩

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抄録
内容記述タイプ Abstract
内容記述 Background: We found inter-scanner differences in dopamine receptor imaging. In order to evaluate different effects of physical performances on tracer kinetics images, we tested accuracy in deadtime correction and scatter correction using phantoms mimicked the head and whole body of human subject.
\nMethods: The two PET scanners used were Eminence Sophia (Shimadzu, Corp) and EXACT HR+ (Siemens). Each scanner was tested the following examinations. The deadtime correction was tested using Hoffman phantom filled by 3mCi C-11 radioactivity. The effects of the scatter emitted from the whole bogy were evaluated using three uniform pool phantoms, one inside of FOV mimicking the head and two outside of FOV mimicking the whole body. These pools are filled by 3 mCi of [C-11] radioactivity for the inside of FOV and two of 12 mCi for the outside FOV. Dynamic scan were performed over 4 hours. Images were reconstructed by the filtered back-projection method. Images were analyzed using PMOD.
\nResults: Both PET scanners did not show any significant systematic errors in the deadtime correction. The existence of a massive (8 times) radioactivity in the outside the FOV was overestimated image concentrations of the pool at the inside FOV by 10% in Eminence, and this overestimation was continued till the radioactivity was decayed. However, the overestimation was reduced less than a few percent after software correction. In HR+ scanner, the same experiment resulted in the underestimation of the image concentration by 10-20% for the early phase but the underestimation was become negligible in late phase.
\nConclusions: The phantom studies mimicking the head and whole body for the receptor imaging did not explain the inter-scanner difference in dopamine imaging
会議概要(会議名, 開催地, 会期, 主催者等)
内容記述タイプ Other
内容記述 The 9th International Symposium on Functional Neuroreceptor Mapping of the Living Brain (NRM12)
発表年月日
日付 2012-08-11
日付タイプ Issued
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