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Evaluation of Inter-Scanner Differences in Effect of Radioactivity from Outside FOV
https://repo.qst.go.jp/records/70850
https://repo.qst.go.jp/records/70850d78e1495-975d-46cc-aa5e-05cbcfd43532
Item type | 会議発表用資料 / Presentation(1) | |||||
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公開日 | 2012-08-17 | |||||
タイトル | ||||||
タイトル | Evaluation of Inter-Scanner Differences in Effect of Radioactivity from Outside FOV | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_c94f | |||||
資源タイプ | conference object | |||||
アクセス権 | ||||||
アクセス権 | metadata only access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
著者 |
Shiraishi, Takahiro
× Shiraishi, Takahiro× Kimura, Yasuyuki× Kanno, Iwao× Suhara, Tetsuya× Ito, Hiroshi× 白石 貴博× 木村 泰之× 菅野 巖× 須原 哲也× 伊藤 浩 |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Background: We found inter-scanner differences in dopamine receptor imaging. In order to evaluate different effects of physical performances on tracer kinetics images, we tested accuracy in deadtime correction and scatter correction using phantoms mimicked the head and whole body of human subject. \nMethods: The two PET scanners used were Eminence Sophia (Shimadzu, Corp) and EXACT HR+ (Siemens). Each scanner was tested the following examinations. The deadtime correction was tested using Hoffman phantom filled by 3mCi C-11 radioactivity. The effects of the scatter emitted from the whole bogy were evaluated using three uniform pool phantoms, one inside of FOV mimicking the head and two outside of FOV mimicking the whole body. These pools are filled by 3 mCi of [C-11] radioactivity for the inside of FOV and two of 12 mCi for the outside FOV. Dynamic scan were performed over 4 hours. Images were reconstructed by the filtered back-projection method. Images were analyzed using PMOD. \nResults: Both PET scanners did not show any significant systematic errors in the deadtime correction. The existence of a massive (8 times) radioactivity in the outside the FOV was overestimated image concentrations of the pool at the inside FOV by 10% in Eminence, and this overestimation was continued till the radioactivity was decayed. However, the overestimation was reduced less than a few percent after software correction. In HR+ scanner, the same experiment resulted in the underestimation of the image concentration by 10-20% for the early phase but the underestimation was become negligible in late phase. \nConclusions: The phantom studies mimicking the head and whole body for the receptor imaging did not explain the inter-scanner difference in dopamine imaging |
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会議概要(会議名, 開催地, 会期, 主催者等) | ||||||
内容記述タイプ | Other | |||||
内容記述 | The 9th International Symposium on Functional Neuroreceptor Mapping of the Living Brain (NRM12) | |||||
発表年月日 | ||||||
日付 | 2012-08-11 | |||||
日付タイプ | Issued |