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  1. 学会発表・講演等
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Synthesis and Radical-Scavenging Activity of Planar Catechin Derivatives with Various Amino Acids as a Promising Antioxidant

https://repo.qst.go.jp/records/70656
https://repo.qst.go.jp/records/70656
9638ea72-ab32-4be4-8fd2-a6fbce9a6206
Item type 会議発表用資料 / Presentation(1)
公開日 2011-12-05
タイトル
タイトル Synthesis and Radical-Scavenging Activity of Planar Catechin Derivatives with Various Amino Acids as a Promising Antioxidant
言語
言語 eng
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_c94f
資源タイプ conference object
アクセス権
アクセス権 metadata only access
アクセス権URI http://purl.org/coar/access_right/c_14cb
著者 Imai, Kohei

× Imai, Kohei

WEKO 694040

Imai, Kohei

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Nakanishi, Ikuo

× Nakanishi, Ikuo

WEKO 694041

Nakanishi, Ikuo

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Nakanishi, Satomi

× Nakanishi, Satomi

WEKO 694042

Nakanishi, Satomi

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Takagaki, Ryohei

× Takagaki, Ryohei

WEKO 694043

Takagaki, Ryohei

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Ozawa, Toshihiko

× Ozawa, Toshihiko

WEKO 694044

Ozawa, Toshihiko

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Okuda, Haruhiro

× Okuda, Haruhiro

WEKO 694045

Okuda, Haruhiro

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Miyata, Naoki

× Miyata, Naoki

WEKO 694046

Miyata, Naoki

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Matsumoto, Kenichiro

× Matsumoto, Kenichiro

WEKO 694047

Matsumoto, Kenichiro

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Nakamura, Asao

× Nakamura, Asao

WEKO 694048

Nakamura, Asao

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Fukuhara, Kiyoshi

× Fukuhara, Kiyoshi

WEKO 694049

Fukuhara, Kiyoshi

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中西 郁夫

× 中西 郁夫

WEKO 694050

en 中西 郁夫

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松本 謙一郎

× 松本 謙一郎

WEKO 694051

en 松本 謙一郎

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抄録
内容記述タイプ Abstract
内容記述 Radical-scavenging reactivities of newly synthesized 7 planar catechin derivatives substituted by an amino acid, which is lysine, arginine, histidine, asparagine acid, glutamic acid, serine, or cysteine, have been examined by the quenching kinetics of galvinoxyl radical in an acetonitrile solution observed by stopped flow technique. Among the derivatives, one bearing arginine moiety showed an approximate 670-fold enhanced radical-scavenging activity than naturally occurring (+)-catechin, which is due to the strong intramolecular hydrogen bonding between the amino acid and catechin moieties.
会議概要(会議名, 開催地, 会期, 主催者等)
内容記述タイプ Other
内容記述 8th AFMC International Medicinal Chemistry Symposium (AIMECS 11)
発表年月日
日付 2011-12-02
日付タイプ Issued
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