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Meta-Analysis of Second Cancer Risk after Radiotherapy among Childhood Cancer Survivors
https://repo.qst.go.jp/records/70142
https://repo.qst.go.jp/records/701426e96f494-8eab-4ffa-a832-35b37a02059d
| Item type | 会議発表用資料 / Presentation(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2010-06-02 | |||||
| タイトル | ||||||
| タイトル | Meta-Analysis of Second Cancer Risk after Radiotherapy among Childhood Cancer Survivors | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_c94f | |||||
| 資源タイプ | conference object | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Doi, Kazutaka
× Doi, Kazutaka× Mieno, Makiko× Shimada, Yoshiya× Yonehara, Hidenori× Yoshinaga, Shinji× 土居 主尚× 三重野 牧子× 島田 義也× 米原 英典× 吉永 信治 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | We have conducted a meta-analysis of studies on the excess relative risk per Gy (ERR) of second cancer before, but the small number of eligible studies restricted quantitative evaluations. To solve this problem, a method to calculate ERR per Gy estimates from another form of estimates was developed, and a meta-analysis was conducted again. We searched the PubMed database, and 26 studies were identified. ERR per Gy estimates were available in 15 studies, and for rest 11 studes, we used the regression model to calculate ERR per Gy estimates from other estimates. The overall ERR per Gy estimate was 0.61 (95% CI: 0.31, 1.2), which was much lower than that of atomic bomb survivors exposed as young children (1.7; 95%CI: 1.1, 2.5). Heterogeneity of the ERR per Gy estimates among studies was suggested, and the reasons were explored. It was suggested that ERR per Gy estimates in the different SMN sites differed greatly, and they also decreased to 0.88 time by one year increase in primary cancer age. The heterogeneity could be explained by the SMN sites and primary cancer age to some extent. | |||||
| 会議概要（会議名, 開催地, 会期, 主催者等） | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | The Third Asian and Oceanic Congree on Radiation Protection | |||||
| 発表年月日 | ||||||
| 日付 | 2010-05-28 | |||||
| 日付タイプ | Issued | |||||
