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Application of Monte Carlo method to treatment planning for carbon ion therapy using scanning irradiation system

https://repo.qst.go.jp/records/70099
https://repo.qst.go.jp/records/70099
ade01ece-7226-4bae-97a4-6defea69f319
Item type 会議発表用資料 / Presentation(1)
公開日 2010-05-24
タイトル
タイトル Application of Monte Carlo method to treatment planning for carbon ion therapy using scanning irradiation system
言語
言語 eng
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_c94f
資源タイプ conference object
アクセス権
アクセス権 metadata only access
アクセス権URI http://purl.org/coar/access_right/c_14cb
著者 Toshitou, Toshiyuki

× Toshitou, Toshiyuki

WEKO 688371

Toshitou, Toshiyuki

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WEKO 688372

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抄録
内容記述タイプ Abstract
内容記述 アブストラクト
Propose
We have developed a Monte Carlo simulation software to calculate dose distributions for carbon ion therapy using a scanning irradiation system. It is capable of high precision calculations and will be applied for treatment planning.
Methods
The software is developed by extending the functions of the PTSsim, which is a Geant4 based Monte Carlo simulation framework for particle therapy, and able to handle CT image data in DICOM format. We created a new C++ library to describe the scanning irradiation system being developed at HIMAC at the National Institute of Radiological Sciences in Chiba, Japan. Moreover, models to compute the relative biological effectiveness from physical doses and radiation quality are built to obtain biological dose distributions.
Results
We verified the simulations by comparing simulated physical dose distributions of pencil beams in water phantom with experimental measurements for 230, 290 and 350 MeV/n carbon beams. We found that our simulations could reproduce the measurements well after a modification of a few parameters used to simulate electromagnetic processes in Geant4. Verifications for more complicated geometries are making progress now.
Also Monte Carlo simulations for the patients' CT images and comparisons with analytical calculations have been performed.
Conclusions
We have built a Monte Carlo simulation software for a carbon ion scanning irradiation system. The software is able to calculate both physical and biological dose distributions in geometries defined by CT image data. The Accuracy of the simulations is found to be acceptable for applications to treatment planning. We will establish a way to apply it to practical treatment planning by using our developed software.
会議概要(会議名, 開催地, 会期, 主催者等)
内容記述タイプ Other
内容記述 PTCOG49
発表年月日
日付 2010-05-22
日付タイプ Issued
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