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Short-course carbon ion radiotherapy for patients with hepatocellular carcinoma
https://repo.qst.go.jp/records/70097
https://repo.qst.go.jp/records/700977902c6cb-2b78-4cf1-ae11-2191e8a95d32
| Item type | 会議発表用資料 / Presentation(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2010-05-24 | |||||
| タイトル | ||||||
| タイトル | Short-course carbon ion radiotherapy for patients with hepatocellular carcinoma | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_c94f | |||||
| 資源タイプ | conference object | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Imada, Hiroshi
× Imada, Hiroshi× Yasuda, Shigeo× Yamada, Shigeru× Shinoto, Makoto× Oonishi, Kazuhiko× Kamada, Tadashi× Tsujii, Hirohiko× 今田 浩史× 安田 茂雄× 山田 滋× 篠藤 誠× 大西 和彦× 鎌田 正× 辻井 博彦 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Purpose: To evaluate the safety and efficacy of the short-course carbon ion radiotherapy (C-ion RT) of 52.8 GyE in 4 fractions for hepatocellular carcinoma (HCC). Methods: Sixty-nine patients were enrolled. Eligibility criteria were as follows: biopsy-proven HCC; recurrent or residual tumor after other ineffective treatments or no indication for any other treatment; no tumor thrombosis of the portal main branch; no other viable lesion outside the planning target volume; no prior radiotherapy for target tumors; hepatic disorder of Child-Pugh classification A or B; Karnofsky performance status of 60-100; no other active cancer; and digestive tract not in contact with clinical target volume. The total dose delivered was 52.8 GyE in 4 fractions for 1 week. The dose per fraction was 13.2 GyE. Results: No hepatic failure resulting from the therapy and no treatment-related death occurred. In 91% and 90% of patients, the Child-Pugh score did not increase by more than 1 point in the early and late phase, respectively. The 5-year overall survival and local control rates were 31% and 94%, respectively. In patients with suitable stage for hepatic resection, that is, a single lesion of 3 to 5 cm in diameter and Child-Pugh classification A liver function, overall survival rate was 69% at 5 years. Conclusions: In most of patients with HCC, short-course C-ion RT does not reduce liver function. It seems to be a minimally invasive and effective therapy for HCC. | |||||
| 会議概要（会議名, 開催地, 会期, 主催者等） | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | 第49回粒子線治療世界会議 | |||||
| 発表年月日 | ||||||
| 日付 | 2010-05-22 | |||||
| 日付タイプ | Issued | |||||
