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Short-course carbon ion radiotherapy for patients with hepatocellular carcinoma

https://repo.qst.go.jp/records/70097
https://repo.qst.go.jp/records/70097
7902c6cb-2b78-4cf1-ae11-2191e8a95d32
Item type 会議発表用資料 / Presentation(1)
公開日 2010-05-24
タイトル
タイトル Short-course carbon ion radiotherapy for patients with hepatocellular carcinoma
言語
言語 eng
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_c94f
資源タイプ conference object
アクセス権
アクセス権 metadata only access
アクセス権URI http://purl.org/coar/access_right/c_14cb
著者 Imada, Hiroshi

× Imada, Hiroshi

WEKO 688355

Imada, Hiroshi

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Yasuda, Shigeo

× Yasuda, Shigeo

WEKO 688356

Yasuda, Shigeo

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Yamada, Shigeru

× Yamada, Shigeru

WEKO 688357

Yamada, Shigeru

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Shinoto, Makoto

× Shinoto, Makoto

WEKO 688358

Shinoto, Makoto

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Oonishi, Kazuhiko

× Oonishi, Kazuhiko

WEKO 688359

Oonishi, Kazuhiko

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Kamada, Tadashi

× Kamada, Tadashi

WEKO 688360

Kamada, Tadashi

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Tsujii, Hirohiko

× Tsujii, Hirohiko

WEKO 688361

Tsujii, Hirohiko

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今田 浩史

× 今田 浩史

WEKO 688362

en 今田 浩史

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安田 茂雄

× 安田 茂雄

WEKO 688363

en 安田 茂雄

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山田 滋

× 山田 滋

WEKO 688364

en 山田 滋

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篠藤 誠

× 篠藤 誠

WEKO 688365

en 篠藤 誠

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大西 和彦

× 大西 和彦

WEKO 688366

en 大西 和彦

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鎌田 正

× 鎌田 正

WEKO 688367

en 鎌田 正

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辻井 博彦

× 辻井 博彦

WEKO 688368

en 辻井 博彦

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内容記述タイプ Abstract
内容記述 Purpose: To evaluate the safety and efficacy of the short-course carbon ion radiotherapy (C-ion RT) of 52.8 GyE in 4 fractions for hepatocellular carcinoma (HCC). Methods: Sixty-nine patients were enrolled. Eligibility criteria were as follows: biopsy-proven HCC; recurrent or residual tumor after other ineffective treatments or no indication for any other treatment; no tumor thrombosis of the portal main branch; no other viable lesion outside the planning target volume; no prior radiotherapy for target tumors; hepatic disorder of Child-Pugh classification A or B; Karnofsky performance status of 60-100; no other active cancer; and digestive tract not in contact with clinical target volume. The total dose delivered was 52.8 GyE in 4 fractions for 1 week. The dose per fraction was 13.2 GyE. Results: No hepatic failure resulting from the therapy and no treatment-related death occurred. In 91% and 90% of patients, the Child-Pugh score did not increase by more than 1 point in the early and late phase, respectively. The 5-year overall survival and local control rates were 31% and 94%, respectively. In patients with suitable stage for hepatic resection, that is, a single lesion of 3 to 5 cm in diameter and Child-Pugh classification A liver function, overall survival rate was 69% at 5 years. Conclusions: In most of patients with HCC, short-course C-ion RT does not reduce liver function. It seems to be a minimally invasive and effective therapy for HCC.
会議概要(会議名, 開催地, 会期, 主催者等)
内容記述タイプ Other
内容記述 第49回粒子線治療世界会議
発表年月日
日付 2010-05-22
日付タイプ Issued
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