WEKO3
アイテム
認知症を伴うレヴィ小体病におけるアミロイドイメージング
https://repo.qst.go.jp/records/69848
https://repo.qst.go.jp/records/6984889eb2c6d-856d-479a-9f5c-549b62f658d9
| Item type | 会議発表用資料 / Presentation(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2009-09-15 | |||||
| タイトル | ||||||
| タイトル | 認知症を伴うレヴィ小体病におけるアミロイドイメージング | |||||
| 言語 | ||||||
| 言語 | jpn | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_c94f | |||||
| 資源タイプ | conference object | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
島田, 斉
× 島田, 斉× 篠遠, 仁× 三好, 美智恵× 平野, 成樹× 佐藤, 康一× 田中, 典子× 黄田, 常嘉× 福士, 清× 入江, 俊章× 伊藤, 浩× 須原, 哲也× 島田 斉× 篠遠 仁× 三好 美智恵× 平野 成樹× 佐藤 康一× 田中 典子× 黄田 常嘉× 福士 清× 入江 俊章× 伊藤 浩× 須原 哲也 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Abstract: Background and aims: Dementia with Lewy bodies (DLB) is the second most frequent neurodegenerative dementia, after Alzheimer’s disease (AD). DLB is diagnosed when dementia occurs before or concurrently with parkinsonism, while Parkinson’s disease with dementia (PDD) is diagnosed when dementia occurs in the context of well-established PD. Until now, there has been debate over whether PDD and DLB are one disease with different phenotypic expressions or two different diseases. To elucidate whether PDD and DLB are different or not from the point of view of beta-amyloid burden, we investigated the pattern of beta-amyloid deposition in patients with DLB, PDD and AD by PET. Methods: Participants were 7 patients with DLB (mean age: 79.1+/-3.7 years; MMSE: 20.3+/-3.9), 7 PDD (mean age: 70.9+/-7.0 years; MMSE: 21.8+/-2.3), 10 late-onset AD (mean age: 76.5+/-4.7 years; MMSE: 20.7+/-3.1) and age-matched 10 healthy controls (mean age: 70.4+-9.4 years; MMSE: 28.1+-2.1). A dose (about 10mCi) of [11C]-PIB was intravenously injected and sequential PET scans were performed for 90min. We estimated the distribution volume ratio (DVR) using Logan graphical analysis. |
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| 会議概要（会議名, 開催地, 会期, 主催者等） | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | 第32回日本神経科学大会 | |||||
| 発表年月日 | ||||||
| 日付 | 2009-09-18 | |||||
| 日付タイプ | Issued | |||||
