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Four-Dimensional Carbon Ion Dose Assessment in Respiratory-Gated Lung Therapy: Simulation Study in Respiratory Pattern Variation Cases

https://repo.qst.go.jp/records/69820
https://repo.qst.go.jp/records/69820
6cb8fa36-97b3-4121-a87e-2fdee614bdba
Item type 会議発表用資料 / Presentation(1)
公開日 2009-08-04
タイトル
タイトル Four-Dimensional Carbon Ion Dose Assessment in Respiratory-Gated Lung Therapy: Simulation Study in Respiratory Pattern Variation Cases
言語
言語 eng
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_c94f
資源タイプ conference object
アクセス権
アクセス権 metadata only access
アクセス権URI http://purl.org/coar/access_right/c_14cb
著者 Dobashi, Suguru

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WEKO 685531

Dobashi, Suguru

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土橋 卓

× 土橋 卓

WEKO 685532

en 土橋 卓

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抄録
内容記述タイプ Abstract
内容記述 Purpose: To estimate the effects of the irregular respiratory pattern during the carbon-beam treatment of lung cancer in the four-dimensional treatment planning, we simulated the irregular respiratory motion by the NCAT phantom and calculated the accumulated dose for respiratory gated and ungated treatment. Method and Materials: 4D NCAT phantom was used to simulate the irregular respiratory tumor motion during several cycles of respiration. The treatment planning was performed based on the first cycle of the respiration. The cycle was subdivided into 10 phases and the prescribed dose was distributed so that all points in the planning target volume (PTV) receives more than 90 percent of the total prescribed dose. The total of 52.8 GyE was delivered from four beam ports with angles selected to be 340, 70, 20, and 110 degrees. The plan was scheduled both for ungated and gated treatment. For the respiratory-gated treatment, the gating window was set in T40%–T60% phases. The dose calculation was based on the pencil beam algorithm. The accumulated dose was evaluated and compared between gated- and ungated- results in terms of V20, D95 and dose-volume histogram (DVH). Results: For the ungated case the dose conformation was deteriorated compared to the ideal case where the respiratory pattern was completely the same as in the treatment planning, while, for the gated treatment, the improved dose conformation was observed in terms of both D95 and V20. Conclusion: Though the 4D planning is effective to estimate internal margin, the irregular respiratory pattern may deteriorate the conformation of the accumulated dose during the whole treatment. The gating treatment, if appropriately synchronized, is effective both for the dose conformity and the reduction of the extra dose to the normal tissues or organs at risks.
会議概要(会議名, 開催地, 会期, 主催者等)
内容記述タイプ Other
内容記述 51st AAPM Annual Meeting
発表年月日
日付 2009-07-30
日付タイプ Issued
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