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Multimodal Thermo-Sensitive Polymer-Modified Liposome for Visualization and Treatment of Disseminated Cancer
https://repo.qst.go.jp/records/69743
https://repo.qst.go.jp/records/69743690cc3e8-7fd0-41a9-87c8-71d5ad8a9cae
| Item type | 会議発表用資料 / Presentation(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2009-04-27 | |||||
| タイトル | ||||||
| タイトル | Multimodal Thermo-Sensitive Polymer-Modified Liposome for Visualization and Treatment of Disseminated Cancer | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_c94f | |||||
| 資源タイプ | conference object | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Kokuryo, Daisuke
× Kokuryo, Daisuke× et.al× 國領 大介 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | A drug delivery system using a multimodal thermo-sensitive 'polymer-modified' liposome (MTPL) would be a powerful imaging tool to help avoid the side-effects of chemotherapy on the intact organ. In this study, an accumulation of and thermo-triggered drug release from MTPL were evaluated for disseminated-cancer using MRI and optical imaging. In the ex vivo optical images, the MTPL accumulation in the tumor area increased over 8 hours after the administration. In the T1-weighted MRI, the signal intensities in the bowel and the kidney changed after thermo-triggering. | |||||
| 会議概要（会議名, 開催地, 会期, 主催者等） | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | ISMRM 17th Scientific Meeting & Exhibition | |||||
| 発表年月日 | ||||||
| 日付 | 2009-04-24 | |||||
| 日付タイプ | Issued | |||||
