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Quality assurance in the prospective multi-institutional trial on definitive radiotherapy using high-dose-rate intracavitary brachytherapy for uterine cervical cancer: the individual case review
https://repo.qst.go.jp/records/69470
https://repo.qst.go.jp/records/6947021cdcfee-d40e-4064-9288-377070fd4cd6
| アイテムタイプ | 会議発表用資料 / Presentation(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2008-09-25 | |||||
| タイトル | ||||||
| タイトル | Quality assurance in the prospective multi-institutional trial on definitive radiotherapy using high-dose-rate intracavitary brachytherapy for uterine cervical cancer: the individual case review | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_c94f | |||||
| 資源タイプ | conference output | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Toita, Takafumi
× Toita, Takafumi× Oguchi, Masahiko× Ohno, Tatsuya× Kato, Shingo× Niibe, Yuzuru× Hayakawa, Kazushige× Teshima, Teruki× 小口 正彦× 大野 達也× 加藤 眞吾× 手島 昭樹 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Purpose: To assess the protocol compliance of radiotherapy in the multi-institutional prospective study (JAROG0401) which investigates the efficacy and toxicity of definitive radiotherapy using high-dose rate intracavitary brachytherapy (HDR-ICBT) for patients with early stage uterine cervical cancer. \nMaterials and Methods: Individual case review (ICR) on radiotherapy of all 60 patients entered into the study was performed. Patient data including pretreatment MRI (T2WI), data of external beam radiotherapy (EBRT) (treatment chart, simulation films/ DRR, portal films/ EPID, and dose distributions), and data of HDR-ICBT (treatment chart, AP/ lateral orthogonal films, and isodose distributions for all insertions) were collected by security mails. All radiological images and dose distributions were digitally processed, mounted on Microsoft PowerPoint, in CD-ROM. Other data such as treatment charts were submitted as hard copies. Radiotherapy parameters reviewed were clearly stated in the study protocol. Protocol compliance of radiotherapy was evaluated on 16 items according to the criteria developed. The data were reviewed and evaluated in the quality assurance (QA) committee of the JAROG consisting of participating radiation oncologists. The QA committee was held and ICR was performed for three times during the patient accrual period. ICR results of each QA committee were feedback immediately to the participating institutions. \nResults 38 of the 60 patients (63%) were evaluated "acceptable" for all 16 items according to the criteria. The items provided by quantitative values, such as prescribed doses, some time intervals and overall treatment were well followed. Number of cases evaluated "deviation" decreased by each QA committee; 6/15 in the 1st committee, 7/20 in the 2nd, and 6/25 in the 3rd. 10 patients (17%) were evaluated "deviation" on the method of point A determination. \nConclusion Present ICR demonstrated compliance to protocol of radiotherapy was generally good. Decreasing "deviation" through each QA committee suggested the QA program could improve protocol compliance of radiotherapy. A dummy run or benchmark case evaluation might work effectively for some QA, such as point A determination, in the future multi-institutional study involving HDR-ICBT. |
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| 会議概要（会議名, 開催地, 会期, 主催者等） | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | ESTRO27 | |||||
| 発表年月日 | ||||||
| 日付 | 2008-09-18 | |||||
| 日付タイプ | Issued | |||||
