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Computed tomography-based 3D dose-volume parameters of the rectum and late rectal complications in patients with cervical cancer treated with high-dose-rate intracavitary brachytherapy
https://repo.qst.go.jp/records/69469
https://repo.qst.go.jp/records/69469d171971d-429f-40f4-8137-16e38a003286
| Item type | 会議発表用資料 / Presentation(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2008-09-25 | |||||
| タイトル | ||||||
| タイトル | Computed tomography-based 3D dose-volume parameters of the rectum and late rectal complications in patients with cervical cancer treated with high-dose-rate intracavitary brachytherapy | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_c94f | |||||
| 資源タイプ | conference object | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Kato, Shingo
× Kato, Shingo× 加藤 眞吾 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Purpose: To evaluate the efficacy of CT-based three-dimensional (3D) dose-volume parameters of the rectum as predictors for late rectal complications (LRC) in cervical cancer patients treated with high-dose-rate intracavitary brachytherapy (HDR-ICBT). Methods and Materials: Between January 2000 and December 2004, 84 patients were enrolled in a study of ICBT with CT-based dosimetry. HDR-ICBT was prescribed with standard 2D treatment planning. Patients underwent CT scans for 3D dose distributions. The minimum doses to 0.1cc, 1cc, and 2cc of the most irradiated rectal volumes were derived from the dose-volume histograms. The International Commission of Radiation Units and Measurements (ICRU) rectal point dose was also calculated by conventional method. Total dose (external radiotherapy plus brachytherapy) to the rectum was calculated and was transformed to biologically equivalent doses in 2-Gy fractions with a/B of 3 Gy (D0.1cc, D1cc, D2cc, and DICRU). Correlations between these dosimetric parameters and the rate of LRC were analyzed. \nResults: Strong correlation was observed between D0.1cc-2cc and the incidence of LRC. In contrast, no positive correlation was observed between DICRU and the incidence of LRC \nConclusion: It was suggested that CT-based 3D dose-volume parameters may be more effective than the ICRU rectal point dose for predicting LRC. |
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| 会議概要（会議名, 開催地, 会期, 主催者等） | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | ESTRO27 | |||||
| 発表年月日 | ||||||
| 日付 | 2008-09-18 | |||||
| 日付タイプ | Issued | |||||
