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アイテム
Electron-Transfer Mechanism in the Radical-Scavenging Reaction of Resveratrol
https://repo.qst.go.jp/records/69221
https://repo.qst.go.jp/records/692217d7fa707-d39a-4251-9e4e-4c9517708665
Item type | 会議発表用資料 / Presentation(1) | |||||
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公開日 | 2007-12-07 | |||||
タイトル | ||||||
タイトル | Electron-Transfer Mechanism in the Radical-Scavenging Reaction of Resveratrol | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_c94f | |||||
資源タイプ | conference object | |||||
アクセス権 | ||||||
アクセス権 | metadata only access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
著者 |
Nakanishi, Ikuo
× Nakanishi, Ikuo× Shimada, Tomokazu× Ohkubo, Kei× Manda, Sushma× Urano, Shiro× Okuda, Haruhiro× Miyata, Naoki× Ozawa, Toshihiko× Anzai, Kazunori× Fukuzumi, Shunichi× Ikota, Nobuo× Fukuhara, Kiyoshi× 中西 郁夫× Manda Sushma× 小澤 俊彦× 安西 和紀 |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Resveratrol (1H) has attracted considerable interest with regard to prevention of diseases induced by oxidative stress. However, the radical-scavenging mechanism of 1H has yet to be clarified. On the other hand, 1H has been reported to show genotoxicity in vitro as well as DNA-cleaveing activity in the presence of CuII. We report herein that the scavenging of galvinoxyl radical by 1H is significantly accelerated by the presence of magnesium ion in deaerated acetonitrile. Such an acceleration indicates that the radical-scavenging reaction involves an electron transfer from 1H to galvinoxyl radical, since the electron transfer is known to be accelerated by metal ions. Detailed kinetic data obtained in this study provides valuable information about the development of novel antioxidants with enhanced antioxidative ability and reduced toxicity. |
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会議概要(会議名, 開催地, 会期, 主催者等) | ||||||
内容記述タイプ | Other | |||||
内容記述 | 14th Annual Meeting of the Society for Free Radical Biology and Medicine (SFRBM) | |||||
発表年月日 | ||||||
日付 | 2007-11-19 | |||||
日付タイプ | Issued |