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Electron-Transfer Mechanism in the Radical-Scavenging Reaction of Resveratrol

https://repo.qst.go.jp/records/69221
https://repo.qst.go.jp/records/69221
7d7fa707-d39a-4251-9e4e-4c9517708665
Item type 会議発表用資料 / Presentation(1)
公開日 2007-12-07
タイトル
タイトル Electron-Transfer Mechanism in the Radical-Scavenging Reaction of Resveratrol
言語
言語 eng
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_c94f
資源タイプ conference object
アクセス権
アクセス権 metadata only access
アクセス権URI http://purl.org/coar/access_right/c_14cb
著者 Nakanishi, Ikuo

× Nakanishi, Ikuo

WEKO 679232

Nakanishi, Ikuo

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Shimada, Tomokazu

× Shimada, Tomokazu

WEKO 679233

Shimada, Tomokazu

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Ohkubo, Kei

× Ohkubo, Kei

WEKO 679234

Ohkubo, Kei

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Manda, Sushma

× Manda, Sushma

WEKO 679235

Manda, Sushma

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Urano, Shiro

× Urano, Shiro

WEKO 679236

Urano, Shiro

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Okuda, Haruhiro

× Okuda, Haruhiro

WEKO 679237

Okuda, Haruhiro

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Miyata, Naoki

× Miyata, Naoki

WEKO 679238

Miyata, Naoki

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Ozawa, Toshihiko

× Ozawa, Toshihiko

WEKO 679239

Ozawa, Toshihiko

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Anzai, Kazunori

× Anzai, Kazunori

WEKO 679240

Anzai, Kazunori

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Fukuzumi, Shunichi

× Fukuzumi, Shunichi

WEKO 679241

Fukuzumi, Shunichi

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Ikota, Nobuo

× Ikota, Nobuo

WEKO 679242

Ikota, Nobuo

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Fukuhara, Kiyoshi

× Fukuhara, Kiyoshi

WEKO 679243

Fukuhara, Kiyoshi

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中西 郁夫

× 中西 郁夫

WEKO 679244

en 中西 郁夫

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Manda Sushma

× Manda Sushma

WEKO 679245

en Manda Sushma

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小澤 俊彦

× 小澤 俊彦

WEKO 679246

en 小澤 俊彦

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安西 和紀

× 安西 和紀

WEKO 679247

en 安西 和紀

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抄録
内容記述タイプ Abstract
内容記述 Resveratrol (1H) has attracted considerable interest with regard to prevention of diseases induced by oxidative stress. However, the radical-scavenging mechanism of 1H has yet to be clarified. On the other hand, 1H has been reported to show genotoxicity in vitro as well as DNA-cleaveing activity in the presence of CuII. We
report herein that the scavenging of galvinoxyl radical by 1H is significantly accelerated by the presence of magnesium ion in deaerated acetonitrile. Such an acceleration indicates that the radical-scavenging reaction involves an electron transfer from 1H to galvinoxyl radical, since the electron transfer is known to be accelerated by metal ions. Detailed kinetic data obtained in this study provides valuable information about the development of novel antioxidants with enhanced antioxidative ability and reduced toxicity.
会議概要(会議名, 開催地, 会期, 主催者等)
内容記述タイプ Other
内容記述 14th Annual Meeting of the Society for Free Radical Biology and Medicine (SFRBM)
発表年月日
日付 2007-11-19
日付タイプ Issued
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