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  1. 学会発表・講演等
  2. ポスター発表

CHANGE IN ABSOLUTE OXYGEN CONCENTRATION IN SOLUTION AFTER X-RAY IRRADIATION USING LOW FIELD ELECTRON PARA MAGNETIC RESONANCE SPECTROSCOPY

https://repo.qst.go.jp/records/69191
https://repo.qst.go.jp/records/69191
afabc50e-583a-4467-b63e-ba0ade21f289
Item type 会議発表用資料 / Presentation(1)
公開日 2007-11-26
タイトル
タイトル CHANGE IN ABSOLUTE OXYGEN CONCENTRATION IN SOLUTION AFTER X-RAY IRRADIATION USING LOW FIELD ELECTRON PARA MAGNETIC RESONANCE SPECTROSCOPY
言語
言語 eng
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_c94f
資源タイプ conference object
アクセス権
アクセス権 metadata only access
アクセス権URI http://purl.org/coar/access_right/c_14cb
著者 Matsumoto, Atsuko

× Matsumoto, Atsuko

WEKO 678948

Matsumoto, Atsuko

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Matsumoto, Kenichiro

× Matsumoto, Kenichiro

WEKO 678949

Matsumoto, Kenichiro

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Manda, Sushma

× Manda, Sushma

WEKO 678950

Manda, Sushma

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Ueno, Megumi

× Ueno, Megumi

WEKO 678951

Ueno, Megumi

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Anzai, Kazunori

× Anzai, Kazunori

WEKO 678952

Anzai, Kazunori

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松本 厚子

× 松本 厚子

WEKO 678953

en 松本 厚子

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松本 謙一郎

× 松本 謙一郎

WEKO 678954

en 松本 謙一郎

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Manda Sushma

× Manda Sushma

WEKO 678955

en Manda Sushma

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上野 恵美

× 上野 恵美

WEKO 678956

en 上野 恵美

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安西 和紀

× 安西 和紀

WEKO 678957

en 安西 和紀

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抄録
内容記述タイプ Abstract
内容記述 Oxygen concentration is an important parameter for radiotherapy. It is believed that oxygen is consumed for reacting with several reactive species when an aqueous sample was irradiated by ionizing radiations. However, we do not know exactly how much free radical is generated and how much oxygen molecules are consumed. In this presentation, we aimed to examine quantitative change of oxygen concentration in water after X-irradiation. The pO2 in aqueous samples was evaluated using electron paramagnetic resonance (EPR) oximetry. Two kinds of solid EPR oximetry probes, i.e. lithium phthalocyanine (LiPc) and lithium octa-n-butoxy-naphthalocyanine (LiNc-BuO) were synthesized and used for this purpose. An aliquot of LiPc or LiNc-BuO was put into a microtube, which was filled with phosphate buffered saline (PBS) or Mili-Q water, sealed, and was X-irradiated for 40 min (128 Gy). Linewidth of LiPc or LiNc-BuO was measured with EPR before and after irradiation. Soon after X-irradiation, pO2 in PBS was found to decrease 31 mmHg (both for LiPc and LiNc-BuO) from the pO2 measured before irradiation (152 and 159 mmHg for LiPc and LiNc-BuO, respectively). Mili-Q water instead of PBS showed the same tendency. The pO2 returned gradually in one day. These findings indicate that free oxygen is transiently consumed by X-irradiation probably by generating free radicals.
会議概要(会議名, 開催地, 会期, 主催者等)
内容記述タイプ Other
内容記述 Society for Free Radical Biology and Medicine
発表年月日
日付 2007-11-18
日付タイプ Issued
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