WEKO3
アイテム
Psedouridine reduces radiation-induced chromosome aberration in human lymphocytes
https://repo.qst.go.jp/records/67803
https://repo.qst.go.jp/records/678034c25a86c-5e9d-4eb2-8b0f-ecb783768ea3
| Item type | 会議発表用資料 / Presentation(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2004-06-02 | |||||
| タイトル | ||||||
| タイトル | Psedouridine reduces radiation-induced chromosome aberration in human lymphocytes | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_c94f | |||||
| 資源タイプ | conference object | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Monobe, Manami
× Monobe, Manami× Ando, Koichi× 物部 真奈美× 安藤 興一 |
|||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | We have previously found that beer drinking reduces chromosome aberrations in lymphocytes irradiated in vitro. In this study, human whole blood was in vitro exposed to 200 kVp X rays or 50 keV/micro.m carbon ions in the presence or absence of beer, ethanol and b-pseudouridine (one of the beer component). All the three agents reduced the chromosome aberrations (dicentric) that were caused by either X rays or carbon ions of 4 Gy. Maximum protection for X rays by ethanol, beer and b-pseudouridine was 64 %, 26 % and 34 %, respectively, while maximum protection for carbon-ion by ethanol, beer and b-pseudouridine was 22 %, 26 % and 32 %, respectively. It is concluded that b-pseudouridine, a nucleotide component of tRNA, is a potent protector for damages caused not only by low radiation but also by high LET radiation. | |||||
| 会議概要（会議名, 開催地, 会期, 主催者等） | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | 9th workshop on Heavy Charged Particles in Biology and Medicine and 3rd ENLIGHT co-ordination meeting | |||||
| 発表年月日 | ||||||
| 日付 | 2003-10-03 | |||||
| 日付タイプ | Issued | |||||
