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Effects of Chekating agents, LIHOPO, DTPP, CAP and CBMIDA on removal of plutonium in rats

https://repo.qst.go.jp/records/67790
https://repo.qst.go.jp/records/67790
824f0846-22dc-48e7-a3fe-872a9548ab40
Item type 会議発表用資料 / Presentation(1)
公開日 2004-05-31
タイトル
タイトル Effects of Chekating agents, LIHOPO, DTPP, CAP and CBMIDA on removal of plutonium in rats
言語
言語 eng
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_c94f
資源タイプ conference object
アクセス権
アクセス権 metadata only access
アクセス権URI http://purl.org/coar/access_right/c_14cb
著者 Fukuda, Satoshi

× Fukuda, Satoshi

WEKO 666099

Fukuda, Satoshi

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Iida, Haruzo

× Iida, Haruzo

WEKO 666100

Iida, Haruzo

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Burgada, Ramon

× Burgada, Ramon

WEKO 666101

Burgada, Ramon

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Bailly, Theodorine

× Bailly, Theodorine

WEKO 666102

Bailly, Theodorine

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Yan, Xueming

× Yan, Xueming

WEKO 666103

Yan, Xueming

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Xie, Yuyuan

× Xie, Yuyuan

WEKO 666104

Xie, Yuyuan

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福田 俊

× 福田 俊

WEKO 666105

en 福田 俊

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飯田 治三

× 飯田 治三

WEKO 666106

en 飯田 治三

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厳 雪銘

× 厳 雪銘

WEKO 666107

en 厳 雪銘

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抄録
内容記述タイプ Abstract
内容記述 The effects of DTPP, CAP, LIHOPO and Ca-DTPA in removing plutonium-239 in rats were examined. Twenty-five female Wistar rats, 8 weeks old, were pre-injected with plutonium in the right femoral muscles and divided into five groups; thereafter rats of four groups were injected intraperitoneally with chelating agent CAP, DTPP, LIHOPO or Ca-DTPA at a dose of 30 mmol/kg, once per day for 3 days, beginning 1 hr after plutonium injection on the first day. The fifth group was used as the control. The 24-hr urine and feces were collected. On day 4, rats were sacrificed to obtain organs and serum. In the DTPP group, high urinary excretion on the first day and low concentrations of Pu in the kidney, spleen, femur and muscle of Pu-injected site were observed, but the effect of DTPP was not superior to those of LIHOPO and Ca-DTPA. The results indicated that LIPOHO was the most effective chelating agent for removing plutonium in rats.
会議概要(会議名, 開催地, 会期, 主催者等)
内容記述タイプ Other
内容記述 11th International Congress of the International Radiation Protection Association
発表年月日
日付 2004-05-28
日付タイプ Issued
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