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19F metabolite imaging for 5-FU dynamics and tissue characterization at 9.4T
https://repo.qst.go.jp/records/67783
https://repo.qst.go.jp/records/67783d9c047a3-b3c1-41cd-9c47-34a8a3300d49
| Item type | 会議発表用資料 / Presentation(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2004-05-25 | |||||
| タイトル | ||||||
| タイトル | 19F metabolite imaging for 5-FU dynamics and tissue characterization at 9.4T | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_c94f | |||||
| 資源タイプ | conference object | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Kanazawa, Yoko
× Kanazawa, Yoko× et.al× 金沢 洋子 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Introduction The target compounds for in vivo clinical evaluation of 5-FU by 19F MRS should be the anabolites Fnuc, F-nucleosides/F-nucleotides, effective species as well as the cause of side effects. To cover wide range of body besides the tumor or related organs for drug dynamics, chemical shift image has advantage over localized MRS. [1,2] However, pH dependence of T2(19F)[2-4] sometimes makes echo acquisition difficult. This work repots the simultaneous 19F chemical shift images of such compounds and T2(19F) distribution of Fnuc by modified fast spin echo. The usage of T2 images for the metabolite quantification and the tissue characterization is discussed. |
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| 会議概要（会議名, 開催地, 会期, 主催者等） | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | 12th Scientific Meeting and Exhibition | |||||
| 発表年月日 | ||||||
| 日付 | 2004-05-21 | |||||
| 日付タイプ | Issued | |||||
