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Study on development of the cerebellar cortex in rats exposed to X-irradiation in utero
https://repo.qst.go.jp/records/67417
https://repo.qst.go.jp/records/67417fd565bea-acfb-4a56-9d23-c4aefa468516
| Item type | 会議発表用資料 / Presentation(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2003-07-28 | |||||
| タイトル | ||||||
| タイトル | Study on development of the cerebellar cortex in rats exposed to X-irradiation in utero | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_c94f | |||||
| 資源タイプ | conference object | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Xue, Zhi Sun
× Xue, Zhi Sun× Takahashi, Sentaro× Zhang, Rui× Cui, Chun× Kubota, Yoshihisa× Sato, Hiroshi× Sawada, Kazuhiko× Fukui, Yoshihiro× 孫 学智× 高橋 千太郎× 久保田 善久× 佐藤 宏 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Development of the cerebellar cortex in the rat prenatal exposed to X-irradiation was studied. Females were exposed to X-ray at a single dose of 2.0 Gy on embyonic day 21. Cerebellar samples from pups were obtained at different postnatal days. Sections from the samples were serially cut off in a sagittal plane, and then incubated with anti-calbindin-D28 K and anti-inositol 1, 4, 5-triphosphate receptor antibody. The settled Purkinje cells were lined up in the monolayer and their dendritic plexus was always oriented perpendicular to the long axis of the lobule in the control rat. However, such Purkinje cells in the posterior lobes of the irradiated rat formed multi-layers, and orientation of their dendritic plexus was disordered. X-irradiation at the end of rat pregnancy might prevent mainly the generation of the Purkinje cell that played important roles for neuronal pathways. | |||||
| 会議概要（会議名, 開催地, 会期, 主催者等） | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | 第26回日本神経科学大会 | |||||
| 発表年月日 | ||||||
| 日付 | 2003-07-25 | |||||
| 日付タイプ | Issued | |||||
