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Registration of SPECT, PET and/or X-ray CT images in patients with lung cancer
https://repo.qst.go.jp/records/67287
https://repo.qst.go.jp/records/67287d4abe54e-21b0-4325-badf-9e10e709530b
| Item type | 会議発表用資料 / Presentation(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2002-11-18 | |||||
| タイトル | ||||||
| タイトル | Registration of SPECT, PET and/or X-ray CT images in patients with lung cancer | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_c94f | |||||
| 資源タイプ | conference object | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Uemura, Koji
× Uemura, Koji× Toyama, Hinako× Miyamoto, Tadaaki× Mori, Yutaka× Yoshikawa, Kyosan× 上村 幸司× 外山 比南子× 宮本 忠昭× 森 豊× 吉川 京燦 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Aim: In order to evaluate the therapeutic gain of heavy ion therapy performed on patients with lung cancer, the regional pulmonary functions and the amount of radio tracer accumulation to the tumor, we are investigated by using the region of interest based on anatomical information obtained from X-ray CT. There are many registration techniques for brain images, but not so much for the other organ images that we have studied registration of chest SPECT, PET and/or X-ray CT images. Materials and Methods: Perfusion, ventilation and blood pool images with Tc99m labeled radiopharmaceuticals and SPECT, tumor images with 11C-methionine and PET and X-ray CT scans were performed on several patients with lung cancer before and after heavy ion therapy. The registrations of SPECT-CT, PET-CT and CT-CT were performed by using AMIR (Automatic Multimodality Image Registration), which was developed by Babak et al. for registration of brain images. In a case of SPECT-CT registration, each of the three functional images was registered to the X-ray CT image, and the accuracy of each registration was compared. In the studies of PET-CT registration, the transmission images and X-ray CT images were registered at first, because the 11C-methionine PET images bear little resemblance to the underlying anatomical images. Next, the emission images were realigned by using the same registration parameters. The X-ray CT images obtained from a single subject at the different time were registered to the first X-ray CT images, respectively. Results: In the SPECT-CT registration, the blood pool-CT registration is the best among three SPECT images in visual inspection by radiologists. In the PET-CT registration, the Transmission-CT registrations got good results. Therefore, Emission-CT registrations also got good results. In the CT-CT registration, the X-ray CT images obtained from a single subject at the different time were superimposed well each other except for lower lobe. As the results, it was found to be possible to evaluate the therapeutic gain of heavy particle therapy sequentially by using the same ROI. Conclusion: This method is useful for evaluating the therapeutic gain of heavy particle therapy performed on patients with lung cancer quantitatively and sequentially. Registration of chest SPECT, PET and/or X-ray CT images by using AMIR method got good result for all of the registrations. |
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| 会議概要（会議名, 開催地, 会期, 主催者等） | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | 8th Congress of the World Federation of Nuclear Medicine & Biology | |||||
| 発表年月日 | ||||||
| 日付 | 2002-10-04 | |||||
| 日付タイプ | Issued | |||||
