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The multiscale dynamics of proteins measured by quasielastic neutron scattering and dynamic light scattering
https://repo.qst.go.jp/records/66945
https://repo.qst.go.jp/records/66945956624b6-bc45-493a-95e6-7989ced6ca46
| Item type | 会議発表用資料 / Presentation(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2018-10-16 | |||||
| タイトル | ||||||
| タイトル | The multiscale dynamics of proteins measured by quasielastic neutron scattering and dynamic light scattering | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_c94f | |||||
| 資源タイプ | conference object | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
藤原, 悟
× 藤原, 悟× 松尾, 龍人× 河野, 史明× 柴田, 薫× 藤原 悟× 松尾 龍人× 河野 史明 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Proteins have a hierarchy of dynamics from local side-chain motions, through segmental and domain motions, to diffusion of the entire molecules. Elucidating how the dynamics at these different scales are related to each other is important for elucidation of the mechanisms of the protein functions. The dynamics at the different scales thus needs to be measured under the same condition. Here we propose a new method to measure the multiscale dynamics of the proteins. Combination of neutron and light scattering distinguishes the local motions, segmental motions, and diffusion of the entire molecules. We applied this method to ribonuclease A in the folded, molten-globule, and unfolded states, and showed that the degrees of the segmental motions are different in these states. | |||||
| 会議概要（会議名, 開催地, 会期, 主催者等） | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | 第56回日本生物物理学会年会 | |||||
| 発表年月日 | ||||||
| 日付 | 2018-09-15 | |||||
| 日付タイプ | Issued | |||||
