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Standardized performance evaluation of a brain-dedicated PET scanner with hemispherical detector arrangement
https://repo.qst.go.jp/records/66838
https://repo.qst.go.jp/records/668387a5be915-e0eb-4878-b7c9-990ab6c939cb
| Item type | 会議発表用資料 / Presentation(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2018-07-03 | |||||
| タイトル | ||||||
| タイトル | Standardized performance evaluation of a brain-dedicated PET scanner with hemispherical detector arrangement | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_c94f | |||||
| 資源タイプ | conference object | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
赤松, 剛
× 赤松, 剛× 田島, 英朗× 岩男, 悠真× 脇坂, 秀克× 前田, 貴雅× 吉田, 英治× 山下, 大地× 山谷, 泰賀× 赤松 剛× 田島 英朗× 岩男 悠真× 脇坂 秀克× 前田 貴雅× 吉田 英治× 山下 大地× 山谷 泰賀 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Purpose: Brain PET imaging is useful for clinical practice and molecular imaging research. High-resolution and high-sensitivity PET systems are highly required for accurate brain functional imaging. Therefore, we have developed a brain-dedicated PET prototype, in which depth-of-interaction (DOI) detectors are arranged to form a hemisphere. On the other hand, some of standardized performance evaluation methods, which are originally proposed for whole-body PET systems, may not be suitable for a next-generation hemispherical brain PET system. Therefore, in this paper, we extended conventional performance evaluation methods so as to be applied to a hemispherical brain PET system. \nMaterials and Methods: The NEMA NU-2 performance evaluation protocol was applied to the prototype, but the NEMA image quality phantom did not fit the prototype. In addition, the Hoffman 3-dimensional brain phantom, which is often used for imaging performance evaluation, did not fit the hemispherical detector arrangement. Therefore, we made a small image quality phantom and a hemispherical Hoffman phantom based on the original phantoms so as not to largely change activity distribution. Then, we experimentally evaluated imaging performance of the prototype, which had 54 four-layer DOI detectors (47 detectors for the hemisphere and the other 7 detectors placed at the back of the neck). We evaluated image quality using our developed small image quality phantom (Six spheres inner diameters: 22, 17, 13, 10, 8 and 5 mm) and hemispherical Hoffman brain phantom. The hot-sphere-to-background activity ratio was 3 which simulating brain tumor PET imaging. We then measured hot-sphere-to-background percent contrast (%contrast) and evaluated gray-to-white matter contrast in comparison with the digital Hoffman phantom. \nResults: The NEMA NU-2 performance evaluation protocol was partially and successfully modified to the prototype. The %contrast of the 8-mm-sphere was 46.9%. The gray-to-white matter contrast was visually better than that of the digital phantom smoothed with 8-mm FWHM Gaussian filter, which has been often used as a reference resolution image. \nConclusion: Standardized performance evaluation methods were successfully extended to hemispherical brain PET scanners by using our newly developed phantoms. We confirmed high imaging performance of our brain PET system. |
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| 会議概要（会議名, 開催地, 会期, 主催者等） | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | 米国核医学会（SNMMI） | |||||
| 発表年月日 | ||||||
| 日付 | 2018-06-26 | |||||
| 日付タイプ | Issued | |||||
