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Analysis of radiation-induced bystander response between human normal cells and cancer cells using SPICE-NIRS microbeam
https://repo.qst.go.jp/records/66830
https://repo.qst.go.jp/records/66830763ec704-4bf0-4563-90c3-3f99f94b59e8
| Item type | 会議発表用資料 / Presentation(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2018-06-18 | |||||
| タイトル | ||||||
| タイトル | Analysis of radiation-induced bystander response between human normal cells and cancer cells using SPICE-NIRS microbeam | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_c94f | |||||
| 資源タイプ | conference object | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Kobayashi, Alisa
× Kobayashi, Alisa× 小林 亜利紗 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | The aim of radiation cancer therapy as an effective tool is to target the tumor accurately, while limiting the exposure to normal tissue. Although the target is the tumor cells, the exposure effect also occurs in the normal tissue surrounding the tumor area. Therefore, it is essential to investigate the intercellular signaling process between irradiated cells and non-irradiated cells in surrounding areas, known as radiation-induced bystander effect. In previous study, we reported that a signal from the bystander normal cells have modulated the DNA double strand breaks (DSB) repair in irradiated cancer cells exhibiting a rescue effect. However, the question arises now is how radiation-induced bystander effect is facilitated? There are two major pathways Gap-junction and Media Transfer. Therefore, in this study we proceed with our previous findings to determine which pathway is involved in rescue effect. | |||||
| 会議概要（会議名, 開催地, 会期, 主催者等） | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | International Open Laboratory Symposium 2018 | |||||
| 発表年月日 | ||||||
| 日付 | 2018-06-15 | |||||
| 日付タイプ | Issued | |||||
