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Neural Mechanisms of illusory self-awareness
https://repo.qst.go.jp/records/66694
https://repo.qst.go.jp/records/666948bd39f8e-10f2-4363-92ae-294d8e83d340
| Item type | 会議発表用資料 / Presentation(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2018-03-26 | |||||
| タイトル | ||||||
| タイトル | Neural Mechanisms of illusory self-awareness | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_c94f | |||||
| 資源タイプ | conference object | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
山田, 真希子
× 山田, 真希子× 山田 真希子 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | The majority of individuals evaluate themselves as superior to the average. This is a cognitive bias, called "the superiority illusion". This illusory self-awareness helps us to have hopes for the future, and has been central to the process of human evolution. Possessing this illusion is also important for mental health, as depressed people appear to have a more realistic perception of themselves, called "depressive realism". I will introduce our studies that revealed spontaneous brain functions and central dopamine neurotransmission that generate this illusion, using resting-state fMRI and PET. A functional connectivity between anterior cingulate cortex (ACC) and striatum regulated by inhibitory dopaminergic neurotransmissions determines individual levels of the superiority illusion in healthy subjects. This finding suggests that dopamine acts on striatal dopamine receptors to suppress ACC-striatal functional connectivity, leading to disinhibited approaches to positive self-evaluation. In contrast, patients with depression did not show superiority illusion, and exhibited heightened ACC-striatal functional connectivity. These findings help us to understand how the illusory self-awareness is biologically determined, and will suggest treatments for depressive realism by targeting specific molecules and neural circuits. | |||||
| 会議概要（会議名, 開催地, 会期, 主催者等） | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | The 94th Annual Meeting of the Physiological Society of Japan | |||||
| 発表年月日 | ||||||
| 日付 | 2017-03-28 | |||||
| 日付タイプ | Issued | |||||
