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Phantom test procedures and criteria for standardization of brain PET imaging across different cameras

https://repo.qst.go.jp/records/66498
https://repo.qst.go.jp/records/66498
ebbff3af-875a-4bbc-bf69-49e0b6d594ef
Item type 会議発表用資料 / Presentation(1)
公開日 2017-11-01
タイトル
タイトル Phantom test procedures and criteria for standardization of brain PET imaging across different cameras
言語
言語 eng
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_c94f
資源タイプ conference object
アクセス権
アクセス権 metadata only access
アクセス権URI http://purl.org/coar/access_right/c_14cb
著者 赤松, 剛

× 赤松, 剛

WEKO 654132

赤松, 剛

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井狩, 彌彦

× 井狩, 彌彦

WEKO 654133

井狩, 彌彦

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脇坂, 秀克

× 脇坂, 秀克

WEKO 654134

脇坂, 秀克

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山谷, 泰賀

× 山谷, 泰賀

WEKO 654135

山谷, 泰賀

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木村, 裕一

× 木村, 裕一

WEKO 654136

木村, 裕一

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織田, 圭一

× 織田, 圭一

WEKO 654137

織田, 圭一

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千田, 道雄

× 千田, 道雄

WEKO 654138

千田, 道雄

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赤松 剛

× 赤松 剛

WEKO 654139

en 赤松 剛

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脇坂 秀克

× 脇坂 秀克

WEKO 654140

en 脇坂 秀克

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山谷 泰賀

× 山谷 泰賀

WEKO 654141

en 山谷 泰賀

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木村 裕一

× 木村 裕一

WEKO 654142

en 木村 裕一

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織田 圭一

× 織田 圭一

WEKO 654143

en 織田 圭一

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抄録
内容記述タイプ Abstract
内容記述 Brain PET imaging technique is valuable for clinical researches as well as for clinical practices. However, image quality and quantitative capability of PET data depend on the PET camera model and the details of acquisition protocol, which makes it a challenge to acquire reliable data in a multicenter clinical study. To make multicenter brain PET data meaningful and to contribute to establishing brain PET as a verified imaging biomarker, we have proposed methods of evaluating absolute quantitative capability, resolution, contrast, uniformity, image noise, etc., using appropriate phantoms for standardization among different camera models. At this moment, we have issued phantom test procedures for brain PET with 11C-methionine, 18F-FDG, and amyloid agents (11C-PiB, 18F-florbetapir, 18F-flutemetamol, and 18F-florbetaben). We first defined the phantom models and the elements of quality that are essential for brain methionine, FDG, and amyloid PET images. Those phantoms that are commercially available and easy to use have been selected: so-called brain tumor phantom for brain methionine PET and Hoffman 3D brain phantom and uniform cylindrical phantom for brain FDG and amyloid PET. Subsequently, we have determined a physical performance indicator and criteria for the phantom tests for each PET drug, which was evaluable and achievable with most of the PET camera models. As a result, these phantom test procedures have been used in a number of multicenter PET studies including Japanese Alzheimer’s Disease Neuroimaging Initiative (J-ADNI). The proposed phantom test and criteria facilitate standardization of brain PET imaging and are useful to validate brain PET scanning performance of the imaging sites.
会議概要(会議名, 開催地, 会期, 主催者等)
内容記述タイプ Other
内容記述 2017 IEEE NSS/MIC
発表年月日
日付 2017-10-28
日付タイプ Issued
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