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頭頸部腫瘍に対する炭素イオン線治療後の口腔-鼻副鼻腔農瘻の危険因子に関する研究

https://repo.qst.go.jp/records/66314
https://repo.qst.go.jp/records/66314
596ed097-3924-481b-8cfe-bc9b44e443ab
Item type 会議発表用資料 / Presentation(1)
公開日 2017-05-08
タイトル
タイトル 頭頸部腫瘍に対する炭素イオン線治療後の口腔-鼻副鼻腔農瘻の危険因子に関する研究
言語
言語 jpn
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_c94f
資源タイプ conference object
アクセス権
アクセス権 metadata only access
アクセス権URI http://purl.org/coar/access_right/c_14cb
著者 小藤, 昌志

× 小藤, 昌志

WEKO 652501

小藤, 昌志

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小藤 昌志

× 小藤 昌志

WEKO 652502

en 小藤 昌志

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抄録
内容記述タイプ Abstract
内容記述 Purpose: The purpose of this study is to determine the risk factors for developing radiation-induced radiation-induced oroantral or oronasal fistula after carbon-ion radiotherapy.
Materials and Methods: Sixty-two patients with oral or sinonasal tumors who were followed up more than 5 years after carbon-ion radiotherapy were included in this study. Thirty patients had nasal tumors, 20 paranasal tumors, and 12 oral tumors. Regarding the histology, 29 patients had mucosal melanoma, 22 adenoid cystic carcinoma, 11 others. Fifteen tumors invaded maxilla. Carbon-ion radiotherapy was delivered to 57.6 Gy (RBE)/16 fractions in 32 patients and 64.0 Gy (RBE)/16 fractions in 30 patients. The clinical factors for the radiation-induced oroantral or oronasal fistula were analyzed using multivariate logistic regression model.
Results: The median follow up period was 88.8 months (range; 60.6-120.7 months). Twenty-three patients (37%) developed the radiation-induced oroantral or oronasal fistula. Multivariate logistic regression analysis showed that maxillary invasion and number of the teeth in the volume receiving more than 50 Gy (RBE) were significant risk factors (p = 0.016 odds ratio 53.9 95% confidence interval [CI] 2.1-1381.0, p = 0.01 odds ratio 2.45% CI 1.2-4.6, respectively).
Conclusions: Maxillary invasion was the strongest predictive factor for developing oroantral or oronasal fistula.
会議概要(会議名, 開催地, 会期, 主催者等)
内容記述タイプ Other
内容記述 平成28年度HIMAC共同利用研究成果発表会
発表年月日
日付 2017-04-17
日付タイプ Issued
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