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Study of dose distribution difference between supine and prone positions in the carbon-ion treatment for the pancreatic tumor

https://repo.qst.go.jp/records/65816
https://repo.qst.go.jp/records/65816
a47a396e-2002-4467-a39e-5eb2b3df3b20
Item type 会議発表用資料 / Presentation(1)
公開日 2015-11-20
タイトル
タイトル Study of dose distribution difference between supine and prone positions in the carbon-ion treatment for the pancreatic tumor
言語
言語 jpn
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_c94f
資源タイプ conference object
アクセス権
アクセス権 metadata only access
アクセス権URI http://purl.org/coar/access_right/c_14cb
著者 三木, 健太朗

× 三木, 健太朗

WEKO 648318

三木, 健太朗

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三木 健太朗

× 三木 健太朗

WEKO 648319

en 三木 健太朗

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抄録
内容記述タイプ Abstract
内容記述 Purpose
The radiation sensitivity of surrounding gastrointestinal organs at risk (OARs) and their close anatomical relationships to the pancreas severely limit target volume margins. When using a fixed irradiation ports, treatment planning needs multiple CT datasets with different patient positions to irradiate from multiple beam angle. Usually, two CT datasets are acquired at supine and prone patient positions, and three or four beam angles are used for the treatment of pancreatic tumor. It needs to consider the variances of dose distribution due to positional morphological changes. Since patient couch can rotate around yaw axis, we can choose supine or prone in the case of horizontal beam irradiation. Therefore, we can select the better position to improve the planning dose distribution. We evaluated dose variations associated with positional morphological changes of organs.
\nMaterials and methods
We retrospectively chose the datasets of 33 patients with pancreatic tumor who underwent CT at supine and prone patient position for carbon-ion therapy. Contours were appropriated from clinical treatment plan, a radiation oncologist manually contoured the gross tumor volume (GTV), planning target volume (CTV), and OARs (duodenum [D1-D2: 1st-2nd portionl; D3-D4: 3rd-4th portion] and stomach). The prescribed dose of 55.2 Gy (RBE) was delivered from four different beam angles (0°, 90°, 180°, and 270°). Dose distributions were calculated using datasets of supine and prone, separately. Patient collimator and compensating boli were designed for each beam. Dose assessments included D95 for GTV and PTV; dose to the most exposed 2 cc volume (D2cc) for the duodenum and stomach; V5 and V10 (volume of the target irradiated with greater than 5 and 10 Gy (RBE)) for the duodenum and stomach in the dose volume histograms (DVHs) for each beam.
\nResult
Dose distribution variances were observed on the most cases between supine and prone. For instance, the stomach located distal side of the tumor in the 90° beam on supine position, it moved proximal side on prone, resulting higher dose irradiation. The positional morphological changes were observed in duodenum also around 0.5 - 1.0 cm between supine and prone. The changes of organ position and dose distribution were various by each patient.
\nConclusion
Optimization of beam angle selection include patient positions can improve the planning dose distribution for pancreatic tumor, sparing OARs.
会議概要(会議名, 開催地, 会期, 主催者等)
内容記述タイプ Other
内容記述 日本放射線腫瘍学会第28回学術大会
発表年月日
日付 2015-11-19
日付タイプ Issued
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