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4D organ motion studies for scanned particle beams at NIRS

https://repo.qst.go.jp/records/65389
https://repo.qst.go.jp/records/65389
5d123b4c-3d44-4022-88ff-0a0a1a387fe4
Item type 会議発表用資料 / Presentation(1)
公開日 2013-12-17
タイトル
タイトル 4D organ motion studies for scanned particle beams at NIRS
言語
言語 eng
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_c94f
資源タイプ conference object
アクセス権
アクセス権 metadata only access
アクセス権URI http://purl.org/coar/access_right/c_14cb
著者 Zenklusen, Silvan Marius

× Zenklusen, Silvan Marius

WEKO 644170

Zenklusen, Silvan Marius

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M, Zenklusen Silvan

× M, Zenklusen Silvan

WEKO 644171

M, Zenklusen Silvan

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森, 慎一郎

× 森, 慎一郎

WEKO 644172

森, 慎一郎

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Zenklusen Silvan Marius

× Zenklusen Silvan Marius

WEKO 644173

en Zenklusen Silvan Marius

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森 慎一郎

× 森 慎一郎

WEKO 644174

en 森 慎一郎

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抄録
内容記述タイプ Abstract
内容記述 Purpose: To treat moving tumors such as in the lung or liver 4DCT imaging is mandatory to understand the motion and to perform an adequate planning. Generally the 4DCT consists of ten 3DCTs associated to ten phases. With this work we wanted to study how many CT phases are required for adequate planning and if they should not be better equally separated in motion amplitude instead of time.
Method: For the numerical NCAT phantom dose distributions for a moving liver tumor have been planned and simulated for various "4DCT resolutions" (spacing between the CT images as a function of the motion amplitude). The resultant dose distributions have been compared and evaluated on target coverage and dose homogeneity. This metrics were used to find an optimal “4DCT resolution” that yielded to a good treatment planning dose distribution while keeping treatment planning manageable in terms of time and effort.
Results: 1mm spacing served as reference case which is though unfeasible in daily practice since it will lead to 21 CT images for a motion amplitude of 1 cm. The dose distributions and target coverage for 2mm and 3mm were closely similar and almost all voxels within the CTV passed the gamma index criteria (3mm, 3% dose) as compared to the reference dose distribution. For larger spacings (4mm, 6mm, ...) the dose distributions started to differ significantly. This is mainly due to a smaller target volume (FTV) used for the planning process and associated range uncertainties caused by a lesser 4DCT resolution.
Conclusion: We are confident to adequately perform 4DCT planning for moving tumors in the liver with a spacing between CT images of about 3mm. For tumors at different sites, such as lung, we will need a separate analysis due to the high variability in density.
会議概要(会議名, 開催地, 会期, 主催者等)
内容記述タイプ Other
内容記述 JRC 2013
発表年月日
日付 2013-04-12
日付タイプ Issued
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