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難治性消化器癌に対する重粒子線と上皮成長因子受容体 (EGFR) 阻害剤併用治療の基礎的検討
https://repo.qst.go.jp/records/65333
https://repo.qst.go.jp/records/65333c4d7ab49-5914-471d-8b86-782362b10519
Item type | 会議発表用資料 / Presentation(1) | |||||
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公開日 | 2013-11-18 | |||||
タイトル | ||||||
タイトル | 難治性消化器癌に対する重粒子線と上皮成長因子受容体 (EGFR) 阻害剤併用治療の基礎的検討 | |||||
言語 | ||||||
言語 | jpn | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_c94f | |||||
資源タイプ | conference object | |||||
アクセス権 | ||||||
アクセス権 | metadata only access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
著者 |
篠藤, 誠
× 篠藤, 誠× 山田, 滋× 篠藤 誠× 山田 滋 |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Aim of present study is toinvestigate the combination effect of carbon ion radiotherapy and epidermal growth factor receptor (EGFR) inhibitor for refractory gastrointestinal carcinoma in mice. We assessed the sensitization effect of gemcitabine and gefitinib (EGFR inhibitor) for carbon ion radiotherapy in tumor ceIls. Gefitinib (Iressa) has been reported to inhibit the proiiferation of pancreatic cancer. And the degree of enhancement of radiation effect is increased with combining GEM and Iressa. ln this study, we investigated the effectiveness of combining GEM and lressa with carbon ion radiotherapy for pancreatic cancer. The addition of GEM and lressa to carbon ion therapy was significantly decreasing the tumor growth in compared to the carbon ion alone. | |||||
会議概要(会議名, 開催地, 会期, 主催者等) | ||||||
内容記述タイプ | Other | |||||
内容記述 | 平成23年度HIMAC共同利用研究成果発表会 | |||||
発表年月日 | ||||||
日付 | 2012-04-24 | |||||
日付タイプ | Issued |