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Dosimetry by Means of In-Beam PET with RI Beam Irradiation
https://repo.qst.go.jp/records/65324
https://repo.qst.go.jp/records/65324919d67f0-ad9a-40d0-b748-7fd054626062
| Item type | 会議発表用資料 / Presentation(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2013-11-15 | |||||
| タイトル | ||||||
| タイトル | Dosimetry by Means of In-Beam PET with RI Beam Irradiation | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_c94f | |||||
| 資源タイプ | conference object | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Nakajima, Yasunori
× Nakajima, Yasunori× Hirano, Yoshiyuki× Tashima, Hideaki× Yoshida, Eiji× Inaniwa, Taku× Satou, Shinji× Yamaya, Taiga× et.al× 中島 靖紀× 平野 祥之× 田島 英朗× 吉田 英治× 稲庭 拓× 佐藤 眞二× 山谷 泰賀 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | In situ visualization of deposited dose distribution is necessary to exploit the advantages of Carbon-ion therapy. Therefore we are developing the world's first, open-type PET "OpenPET" to verify the field irradiated. In addition, a method of utilizing activity measurement in the target irradiated with the beam with positron-emitting radioisotopes (RI) such as 11C and 10C has been proposed. This method has advantage in the amount of activity as well as direct visualization of primary particles themselves, compared with the irradiation with stable nuclei 12C beam. With the RI beam, however, the profile of the dose was still different from that of the activity. Therefore interpretation from activity distribution to dose distribution is necessary to confirm the irradiation field precisely. In this paper, we developed a method of estimating the dose distribution from PET measurements. To utilize the activity measurement of the target, we used the code which calculated the activation distribution and dose distribution taking initial beam energy as a free parameter. Then the maximum likelihood parameter of the initial energy was determined by comparing the measured and the calculated distributions. By using the parameter determined, the dose distribution in the target was calculated as the estimated distribution for the actual one. The uniform PMMA target was irradiated with 11C beam for 10 s. The target was measured from the time beam irradiation started and to 60 s after finishing the irradiation by using a small single-ring OpenPET prototype developed for a proof-of-concept of the in-beam monitoring for charged particle therapy. As a result, the dose distribution, which was originally different from primary particles distribution, was successfully estimated. The peak depth of the estimated dose distribution was in good agreement with the measured dose peak; the estimation error was less than 2 mm. | |||||
| 会議概要（会議名, 開催地, 会期, 主催者等） | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | 2013 IEEE NSS/MIC/PTSD | |||||
| 発表年月日 | ||||||
| 日付 | 2013-11-02 | |||||
| 日付タイプ | Issued | |||||
